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Clarithromycin induced torsade de pointes

Irish Journal of Medical Science volume 177, pages 67–68 (2008)Cite this article

Abstract

Background

Clarithromycin is a commonly used macrolide antibiotic. It is known to cause QT prolongation. Medication induced QT prolongation is a major risk factor for the development of torsade de pointes.

Methods

A 79-year-old lady presented with frequent episodes of torsade de pointes following commencement of clarithromycin. This was noted to be in association with a prolongation of the QT interval.

Conclusion

Knowledge of medications which prolong the QT interval is important to minimize the risk of ventricular arrhythmias, which may lead to sudden death. This is essential in patients with a congenitally long QT interval.

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Author information

Authors and Affiliations

  1. Department of Cardiology, St Vincent’s University Hospital, Elm Park, Dublin 4, Ireland

    C. Hensey & D. Keane

  2. 14 Wilfield Park, Sandymount, Dublin 4, Ireland

    C. Hensey

Authors
  1. C. Hensey
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  2. D. Keane
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Corresponding author

Correspondence to C. Hensey.

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Cite this article

Hensey, C., Keane, D. Clarithromycin induced torsade de pointes. Ir J Med Sci 177, 67–68 (2008). https://doi.org/10.1007/s11845-007-0057-3

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  • DOI: https://doi.org/10.1007/s11845-007-0057-3

Keywords

  • Acquired
  • Clarithromycin
  • Medication
  • Prolongation
  • QT interval
  • Torsade de pointes