Journal of Cancer Survivorship

, Volume 12, Issue 2, pp 256–267 | Cite as

Tai Chi and Qigong for cancer-related symptoms and quality of life: a systematic review and meta-analysis

  • Peter M. Wayne
  • M.S. Lee
  • J. Novakowski
  • K. Osypiuk
  • J. Ligibel
  • L.E. Carlson
  • R. Song
Review

Abstract

Purpose

This study aims to summarize and critically evaluate the effects of Tai Chi and Qigong (TCQ) mind–body exercises on symptoms and quality of life (QOL) in cancer survivors.

Methods

A systematic search in four electronic databases targeted randomized and non-randomized clinical studies evaluating TCQ for fatigue, sleep difficulty, depression, pain, and QOL in cancer patients, published through August 2016. Meta-analysis was used to estimate effect sizes (ES, Hedges’ g) and publication bias for randomized controlled trials (RCTs). Methodological bias in RCTs was assessed.

Results

Our search identified 22 studies, including 15 RCTs that evaluated 1283 participants in total, 75% women. RCTs evaluated breast (n = 7), prostate (n = 2), lymphoma (n = 1), lung (n = 1), or combined (n = 4) cancers. RCT comparison groups included active intervention (n = 7), usual care (n = 5), or both (n = 3). Duration of TCQ training ranged from 3 to 12 weeks. Methodological bias was low in 12 studies and high in 3 studies. TCQ was associated with significant improvement in fatigue (ES = − 0.53, p < 0.001), sleep difficulty (ES = − 0.49, p = 0.018), depression (ES = − 0.27, p = 0.001), and overall QOL (ES = 0.33, p = 0.004); a statistically non-significant trend was observed for pain (ES = − 0.38, p = 0.136). Random effects models were used for meta-analysis based on Q test and I 2 criteria. Funnel plots suggest some degree of publication bias. Findings in non-randomized studies largely paralleled meta-analysis results.

Conclusions

Larger and methodologically sound trials with longer follow-up periods and appropriate comparison groups are needed before definitive conclusions can be drawn, and cancer- and symptom-specific recommendations can be made.

Implications for Cancer Survivors

TCQ shows promise in addressing cancer-related symptoms and QOL in cancer survivors.

Keywords

Tai Chi Qigong Meta-analysis Cancer Fatigue Quality of life 

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Ethical approval

For this type of study formal consent is not required. This article does not contain any studies with human participants or animals performed by any of the authors.

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Copyright information

© Springer Science+Business Media, LLC, part of Springer Nature 2017

Authors and Affiliations

  • Peter M. Wayne
    • 1
  • M.S. Lee
    • 2
  • J. Novakowski
    • 1
  • K. Osypiuk
    • 1
  • J. Ligibel
    • 3
  • L.E. Carlson
    • 4
  • R. Song
    • 5
  1. 1.Osher Center for Integrative MedicineHarvard Medical School and Brigham and Women’s HospitalBostonUSA
  2. 2.Clinical Research DivisionKorea Institute of Oriental MedicineDaejeonRepublic of Korea
  3. 3.Zakim Center for Integrative Therapies and Healthy LivingDana Farber Cancer InstituteBostonUSA
  4. 4.Cumming School of MedicineUniversity of CalgaryCalgaryCanada
  5. 5.College of NursingChungnam National UniversityDaejeonRepublic of Korea

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