Unusual local and distant metastases after complete resection of roentgenographically occult squamous cell carcinoma

Abstract

Roentgenographically occult squamous cell carcinoma (ROSCC) was reported to have been cured after complete resection. We experienced unusual local and distant metastases after complete resection of a ROSCC of left B6 bronchus. During the operation due to the proximal bronchial stump being positive for squamous cell carcinoma (SCC), a left lower sleeve lobectomy was performed. Six years after the operation, a chest CT showed no abnormal shadows. 6 months later a PET-CT showed metastases on bilateral supraclavicular lymph nodes, mediastinal lymph nodes, and the right adrenal glands. A biopsy of the right supraclavicular lymph node revealed that it was a metastatic SCC. The possibility of recurrence from a second pulmonary SCC might still remain. A prolonged follow-up over many years is desirable for a heavy smoker with a ROSCC.

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Acknowledgments

We are grateful to Prof. Sohsuke Yamada (Department of Pathology and Laboratory Medicine, Kanazawa Medical University) and Prof. Yo Niida (Center for Clinical Genomics, Division of Genomic Medicine, Kanazawa Medical University) for supporting this study.

We are grateful to Mr. Dustin Keeling for proofreading this paper.

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Correspondence to Katsuo Usuda.

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Usuda, K., Iwai, S., Yamagata, A. et al. Unusual local and distant metastases after complete resection of roentgenographically occult squamous cell carcinoma. Gen Thorac Cardiovasc Surg (2020). https://doi.org/10.1007/s11748-020-01420-4

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Keywords

  • Roentgenographically occult squamous cell carcinoma
  • Bronchogenic squamous cell carcinoma
  • Early invasive squamous cell carcinoma
  • Recurrence
  • Oncogene