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Mid-term results of mitral valve repair for ischemic mitral regurgitation adjusted according to the degree of remodeling progression

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Abstract

Objectives

Mitral annuloplasty (MAP) for ischemic mitral regurgitation (IMR) with advanced remodeling is often associated with recurrent mitral regurgitation (MR). We performed surgeries adjusted according to the degree of remodeling; i.e., for advanced remodeling cases, we added subvalvular repair (SVR) to MAP. This study aimed to evaluate our experience with patients with IMR.

Methods and results

Thirty patients with IMR (MR grade ≥ 2) were retrospectively analyzed. We performed MAP with SVR for 13 patients (MAP + SVR group) and MAP alone for 17 patients (MAP group). The MAP + SVR group had significantly larger left ventricular dimension and tenting height than the MAP group. Four patients (two in each group) experienced recurrence of MR (MR grade ≥ 2), and the 3-year and 5-year freedom from recurrence of MR rates were 97% and 83%, respectively. Six patients (two in the MAP group and four in the MAP + SVR group) died of cardiac causes during follow-up, and the 3-year and 5-year freedom from cardiac-related death rates were 81% and 74%, respectively. There was no difference between the 2 groups regarding freedom from recurrent MR (p = 0.6) and freedom from cardiac-related death (p = 0.1). The preoperative left ventricular end-systolic dimension was a significant predictor of cardiac death in the multivariate analysis.

Conclusion

Mitral valve repair adjusted according to the degree of remodeling progression provided durable mitral competence; however, it remains unclear if such a strategy is related to a high probability of freedom from cardiac-related death.

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Acknowledgements

We thank Editage (http://www.editage.jp) for English language editing.

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Authors and Affiliations

  1. Department of Cardiovascular Surgery, Miyazaki Medical Association Hospital, Miyazaki, Japan

    Koji Furukawa, Mitsuhiro Yano & Masanori Nishimura

  2. Department of Cardiovascular Surgery, Faculty of Medicine, University of Miyazaki, 5200 Kiyotakecho Kihara, Miyazaki City, Miyazaki, 889-1692, Japan

    Koji Furukawa, Eisaku Nakamura & Kunihide Nakamura

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  1. Koji Furukawa
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  2. Mitsuhiro Yano
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Correspondence to Koji Furukawa.

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Furukawa, K., Yano, M., Nakamura, E. et al. Mid-term results of mitral valve repair for ischemic mitral regurgitation adjusted according to the degree of remodeling progression. Gen Thorac Cardiovasc Surg 66, 707–715 (2018). https://doi.org/10.1007/s11748-018-1000-4

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  • DOI: https://doi.org/10.1007/s11748-018-1000-4

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