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General Thoracic and Cardiovascular Surgery

, Volume 66, Issue 7, pp 415–418 | Cite as

Granulocyte colony stimulating factor-producing lung cancer with severe anemia of inflammation

  • Koutaro Murakami
  • Yujin Kudo
  • Masatoshi Kakihana
  • Jun Matsubayashi
  • Tetsuya Okano
  • Yoshihisa Shimada
  • Toshitaka Nagao
  • Naohiro Kajiwara
  • Tatsuo Ohira
  • Norihiko Ikeda
Original Article
  • 151 Downloads

Abstract

Granulocyte colony stimulating factor (G-CSF)-producing lung cancer occasionally induces severe inflammation with an abnormally high white blood cell count. Herein, we report a 49-year-old man who suffered from resectable G-CSF-producing non-small cell lung cancer with continuous fever and severe anemia. Red blood cell transfusion was necessary for the anemia of inflammation. The patient underwent complete surgical tumor resection. The histopathological diagnosis was a pleomorphic carcinoma at pathological stage IIB. This is apparently the first successful case of surgical resection of G-CSF-producing lung cancer in a patient with severe anemia and uncontrollable fever.

Keywords

G-CSF-producing lung cancer Anemia of inflammation IL-6 

Notes

Acknowledgements

The authors are indebted to Dr. Edward Barroga (http://orcid.org/0000-0002-8920-2607), Associate Professor and Senior Medical Editor from the Department of International Medical Communications of Tokyo Medical University for editing and reviewing the English manuscript. The authors also thank Hitomi Yokota for her skillful technical assistance.

Compliance with ethical standards

Conflict of interest

The authors declare no conflicts of interest associated with this study.

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Copyright information

© The Japanese Association for Thoracic Surgery 2018

Authors and Affiliations

  • Koutaro Murakami
    • 1
  • Yujin Kudo
    • 1
  • Masatoshi Kakihana
    • 1
  • Jun Matsubayashi
    • 2
  • Tetsuya Okano
    • 1
  • Yoshihisa Shimada
    • 1
  • Toshitaka Nagao
    • 2
  • Naohiro Kajiwara
    • 1
  • Tatsuo Ohira
    • 1
  • Norihiko Ikeda
    • 1
  1. 1.Department of SurgeryTokyo Medical UniversityTokyoJapan
  2. 2.Department of Anatomic PathologyTokyo Medical UniversityTokyoJapan

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