General Thoracic and Cardiovascular Surgery

, Volume 66, Issue 4, pp 239–242 | Cite as

A case of atypical type A thymoma with vascular invasion and lung metastasis

  • Naoya Kawakita
  • Kazuya Kondo
  • Hiroaki Toba
  • Akiko Yoneda
  • Hiromitsu Takizawa
  • Akira Tangoku
Case Report


We present a case of type A thymoma with invasion of the left brachiocephalic vein and lung metastases. An 84-year-old man underwent extended thymectomy combined with left brachiocephalic vein reconstruction and resection of a lung metastasis. Histological examination showed vascular invasion by the tumor. The lung metastasis had high mitotic activity and slight nuclear enlargement, the so-called “atypical” features, but the main part of the primary tumor did not. However, the intravascular portion of the tumor had “atypical” histological features like the lung metastasis. It seems that “atypical” histological features are related to clinically malignant behavior.


Thymoma Thymic carcinoma Pathology Lung metastasis 



No funding was provided for this case report.

Compliance with ethical standards

Conflict of interest

All authors declare no conflict of interest associated with this manuscript.


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Copyright information

© The Japanese Association for Thoracic Surgery 2017

Authors and Affiliations

  • Naoya Kawakita
    • 1
  • Kazuya Kondo
    • 2
  • Hiroaki Toba
    • 1
  • Akiko Yoneda
    • 3
  • Hiromitsu Takizawa
    • 1
  • Akira Tangoku
    • 1
  1. 1.Department of Thoracic and Endocrine Surgery and Oncology, Institute of Health BiosciencesThe University of Tokushima Graduate SchoolTokushimaJapan
  2. 2.Department of Oncological Medical Services, Graduate School of Biomedical BiosciencesTokushima UniversityTokushimaJapan
  3. 3.Department of PathologyTokushima University HospitalTokushimaJapan

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