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Data are available on request.
References
Tran T, Delluc A, de Wit C, Petrcich W, Le Gal G, Carrier M (2015) The impact of oral anticoagulation on time to surgery in patients hospitalized with hip fracture. Thromb Res 136(5):962–965
Taranu R, Redclift C, Williams P, Diament M, Tate A, Maddox J, Wilson F, Eardley W (2018) Use of anticoagulants remains a significant threat to timely hip fracture surgery. Geriatr Orthop Surg Rehabil 9:2151459318764150. https://doi.org/10.1177/2151459318764150
Viktil K, Lehre I, Ranhoff AH, Espen M (2019) Serum concentrations and elimination rates of direct-acting oral anticoagulants (DOACs) in older hip fracture patients hospitalized for surgery: a pilot study. Drugs Aging 36:65
Steffel J, Verhamme P, Potpara TS et al (2018) The 2018 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation. Eur Heart J 39(16):1330–1393
Schulman S, Angerås U, Bergqvist D, Eriksson B, Lassen MR, Fisher W (2010) Subcommittee on control of anticoagulation of the scientific and standardization committee of the international society on thrombosis and haemostasis. Definition of major bleeding in clinical investigations of antihemostatic medicinal products in surgical patients. J Thromb Haemost 8:202–204. https://doi.org/10.1111/j.1538-7836.2009.03678.x
Douketis JD, Spyropoulos AC, Duncan J, Carrier M, Le Gal G, Tafur AJ, Vanassche T, Verhamme P, Shivakumar S, Gross PL, Lee AYY, Yeo E, Solymoss S, Kassis J, Le Templier G, Kowalski S, Blostein M, Shah V, MacKay E, Wu C, Clark NP, Bates SM, Spencer FA, Arnaoutoglou E, Coppens M, Arnold DM, Caprini JA, Li N, Moffat KA, Syed S, Schulman S (2019) Perioperative management of patients with atrial fibrillation receiving a direct oral anticoagulant. JAMA Intern Med 179(11):1469–1478. https://doi.org/10.1001/jamainternmed.2019.2431
Squizzato A, Poli D, Barcellona D, Ciampa A, Grandone E, Manotti C, Moia M, Toschi V, Tosetto A, Testa S (2022) Scientific reviewer committee. Management of DOAC in patients undergoing planned surgery or invasive procedure: Italian federation of centers for the diagnosis of thrombotic disorders and the surveillance of the antithrombotic therapies (FCSA) position paper. Thromb Haemost 122(3):329–335. https://doi.org/10.1055/a-1715-5960
Godier A, Dincq AS, Martin AC, Radu A, Leblanc I, Antona M, Vasse M, Golmard JL, Mullier F, Gouin-Thibault I (2017) Predictors of pre-procedural concentrations of direct oral anticoagulants: a prospective multicentre study. Eur Heart J 38(31):2431–2439. https://doi.org/10.1093/eurheartj/ehx403
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The conception and design of the study, or acquisition of data, or analysis and interpretation of data: CR, GMM, AMG. Drafting the article or revising it critically for important intellectual content, CR, RM, RC. Final approval of the version to be submitted. CR, RM, RC.
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This observational prospective study was approved by Ethical Committee Area Vasta Toscana Centro on February 19th 2019 n° 6590/2109.
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Rostagno, C., Mannarino, G.M., Civinini, R. et al. DOACs levels in patients with hip fracture: is there a relation with renal function and time from last drug intake?. Intern Emerg Med (2024). https://doi.org/10.1007/s11739-024-03546-2
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DOI: https://doi.org/10.1007/s11739-024-03546-2