Silybin and metabolic disorders
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Mediterranean diet represents a fundamental strategy in the prevention of cardiovascular and metabolic disorders as demonstrated by observational and interventional trials [ 1]. Among the most represented elements of the Mediterranean diet are polyphenols that display protective effects on cardiometabolic disorders by counteracting oxidative stress that represent a key point of the preventive strategy in this setting. Hence, oxidative stress seems to be involved in both cardiovascular and metabolic disorders [ 2]. Indeed, atherosclerotic disease is associated with increased level of oxidative stress [ 3] as well as metabolic disorders such as non-alcoholic fatty liver disease (NAFLD) [ 4] and diabetes [ 5] (Fig. 1).
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The authors declare that they have no conflict of interest.
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This article does not contain any studies with human participants or animals performed by any of the authors.
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