Internal and Emergency Medicine

, Volume 13, Issue 5, pp 673–678 | Cite as

Emergency Department influenza vaccination campaign allows increasing influenza vaccination coverage without disrupting time interval quality indicators

  • Enrique CasalinoEmail author
  • Aiham Ghazali
  • Donia Bouzid
  • Stephanie Antoniol
  • Philippe Kenway
  • Laurent Pereira
  • Christophe Choquet
  • Emergency Department Study Group on Respiratory Viruses


To evaluate the impact of an influenza vaccination (IV) coverage (IVC) in a vaccination campaign of an Emergency Department (EDVC) and its impact on ED time interval quality indicators. We conducted a 4 year observational study, with an intervention during the 4th year. IVC was calculated during pre-and early-epidemic periods. During the final period, a 12 weeks EDVC was implemented. Physicians and nurses were trained and sensitized in the importance of vaccination, and their role in the prevention of severe forms of influenza was reinforced. The vaccine was proposed by physicians and nurses, and delivered by them. Repeated measures ANOVA is a validated method for related not independent groups ( Overall, IVC was 987/3191 (30.9%) with an increasing trend from 28.8 to 33.2%. In the fourth period, out of 868 patients identified with IV indication, 288 had already been vaccinated (IVC 33.2%). After excluding patients presenting criteria of exclusion, IV was proposed to 475 patients: 317 (66.7%) accepted. The vaccination rate after patient’s acceptance was 89.6% (288/317). At the end of the EDVC, influenza vaccination coverage was 572 (284 + 288)/868 (65.9%). The delay between arrival at the ED and seeing the triage nurse and physician as well as the overall ED length of stay were not modified during the study period and before and during EDVC. EDVC effectively doubled the influenza vaccination coverage, without modifying ED time interval quality indicators.


Influenza Seasonal epidemic Vaccination Coverage Evaluation Interventional study 



We would like to thank Jeffrey Arsham for having reviewed the English language text.

ED-Study Group on Respiratory Viruses: Julien Bernard, MD; Anne Casaubieilh, Nurse Practitioner; Abigael Debit, MD; Elise Dupeyrat, MD; Yoan Gil, MD; Madline Gillo, Nurse Practitioner; Suzanne Goncalves, Nurse Practitioner; Neila Laurent, Head Staff Nurse; Michèle Macaux, Head Staff Nurse; Jeanne Pigeau, Head Staff Nurse; Ranaivoson Michel, MD; Sabrina Rouleau, Head Staff Nurse; Lydia Roux, Head Staff Nurse.

Author contributions

EC, AG, DB, SA, PhK CC and LP conceived the study and designed the trial. EC, AG, DB, SA, PhK CC and LP supervised the conduct of the trial and data collection. EC, AG, DB, SA, PhK CC and LP undertook recruitment of patients and managed the data, including quality control. EC, AG, DB and SA provided statistical advice on study design and analysed the data. EC, AG, DB and PhK drafted the manuscript, and all authors contributed substantially to its revision. EC takes responsibility for the paper as a whole.



Compliance with ethical standards

Conflict of interest


Statements on human and animal rights

The protocol was conducted in agreement with the Helsinki declaration. This dataset was completely anonymous and did not contain any identifiable personal health information. This study was approved by the ED (Assistance Publique-Hôpitaux de Paris) committees on ethics, research and informatics.

Informed consent

Patient informed consent was obtained before study inclusion.


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Copyright information

© SIMI 2018

Authors and Affiliations

  • Enrique Casalino
    • 1
    • 2
    • 3
    • 4
    Email author
  • Aiham Ghazali
    • 1
    • 2
    • 3
  • Donia Bouzid
    • 1
    • 2
    • 3
  • Stephanie Antoniol
    • 1
    • 2
    • 3
  • Philippe Kenway
    • 1
  • Laurent Pereira
    • 1
  • Christophe Choquet
    • 1
  • Emergency Department Study Group on Respiratory Viruses
  1. 1.Emergency Department, Assistance Publique-Hôpitaux de Paris (AP-HP)Groupe Universitaire Paris Nord Val de SeineParisFrance
  2. 2.EA 7334, “Recherche Clinique Coordonnée Ville-Hôpital, Méthodologies et Société (REMES)”, Sorbonne Paris CitéUniversité Paris DiderotParisFrance
  3. 3.Study Group for Efficiency and Quality of Emergency Departments and Non-Scheduled Activities DepartmentsParisFrance
  4. 4.Hôpital BichatParisFrance

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