A mysterious abdominal pain during active psoriasis
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Dr. Damiani and Dr. Della Valle
A 48-year-old woman was admitted to the dermatology department because of erythroderma and psoriasis vulgaris. This patient presented also asthenic, myalgic with 38 °C fever and shivering.
Clinical history and physical examination
Dr. Carrera and Dr. Damiani
The Medical history was characterized by 17 years of psoriasis and psoriatic arthritis with recurrent sudden flares of generalized pustular eruptions, heralded a few days before by systemic symptoms such as fever, epigastric tenderness, vomiting, and occasionally jaundice. Systemic symptoms attenuated when psoriasis therapies were introduced. These symptoms were previously interpreted as related to gastroesophageal reflux that was detected by upper endoscopy, and subsequently treated, and viral gastroenteritis. In each reactivation, hepatitis viruses A, B, C, EBV and HIV were excluded because of blood cultures and negative serology. Urine cultures were negative too. She displayed...
KeywordsPsoriasis Generalized pustular psoriasis Autoinflammation Skin
Compliance with ethical standards
Conflict of interest
Authors declare that they have no conflict of interests.
Statement of human and animal rights
All procedures performed in the present study involving human being were in accordance with the ethical standards of institutional and national research committee and with 1964 Helsinki declaration and its later amendments or comparable ethical standards.
Informed consent was obtained from the patient.
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