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Internal and Emergency Medicine

, Volume 12, Issue 1, pp 69–73 | Cite as

A thrombotic storm

  • Sarah DamantiEmail author
  • Andrea Artoni
  • Tiziano Lucchi
  • Pier Mannuccio Mannucci
  • Daniela Mari
  • Luigi Bergamaschini
IM - CASE RECORD

Case presentation

Dr. Damanti, Professor Bergamaschini

A 72-year-old woman was admitted to a Geriatric Rehabilitation Unit for prosthetic right leg training. She was a nulliparous widow without siblings. Her familiar history was negative for early cardiovascular events.

Her personal history was negative for smoking, hypercholesterolemia, diabetes and hypertension.

At the age of 21, after appendectomy, she developed a left saphenous thrombophlebitis, and since then she has suffered from chronic venous insufficiency with recurrent ulcers, often complicated by bacterial infections, for which she was treated with several antibiotics and with numerous skin grafts without achieving a complete resolution of the problem. At the age of 33, she underwent left saphenectomy, and at the age of 37 she developed a left femoral popliteal deep vein thrombosis which was treated with anticoagulants for a few months.

At the age of 64, a very wide left lower limb ulcerated lesion was investigated with a...

Keywords

Atorvastatin Ticlopidine Thrombophilia Arterial Thrombosis Indeterminate Colitis 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Abbreviations

FVa

Activated factor V

FVIIIa

Activated factor VIII

ACA

Anti-centromere antibodies

ANA

Anti-nuclear antibody

ANCA

Anti-neutrophil cytoplasmic antibody

C3

Complement component 3 (C3)

C4

Complement component 4 (C4)

ENA

Extractable nuclear antigens

FII

Factor II

FV

Factor V

FVIII

Factor VIII

HDL

High density lipoprotein

HDL-C

High density lipoprotein cholesterol

IBD

Inflammatory bowel disease

LDL-C

Low density lipoprotein cholesterol

PT

Prothrombin time

aPTT

Activated partial thromboplastin time

r.v.

Reference values

VTE

Venous thromboembolism

Notes

Compliance with ethical standards

Conflict of interest

The authors declare that they have no conflict of interest.

Statement of human and animal rights

This article does not contain any studies with animals performed by any of the authors.

Informed consent

For this type of study formal consent is not required.

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Copyright information

© SIMI 2016

Authors and Affiliations

  • Sarah Damanti
    • 1
    • 2
    Email author
  • Andrea Artoni
    • 3
  • Tiziano Lucchi
    • 1
  • Pier Mannuccio Mannucci
    • 3
  • Daniela Mari
    • 1
    • 2
  • Luigi Bergamaschini
    • 4
    • 5
  1. 1.Geriatric Unit IRCCS Ca’ Granda Ospedale Maggiore PoliclinicoMilanItaly
  2. 2.Department of Medical Sciences and Community HealthUniversità degli Studi di MilanoMilanItaly
  3. 3.A.Bianchi Bonomi Hemophilia and Thrombosis CenterFondazione IRCCS Ca’ Granda-Ospedale Maggiore PoliclinicoMilanItaly
  4. 4.Department of Biomedical and Clinical Sciences “Luigi Sacco”Università degli Studi di MilanoMilanItaly
  5. 5.A.S.P. Pio Albergo TrivulzioMilanItaly

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