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Short-term prospective study of prescribed physical activity in kidney transplant recipients

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Abstract

Regular physical exercise plays a role in improving cardiovascular and muscular fitness in many metabolic diseases. This study aims to verify any possible benefits, including the eventual influence on any associated risk factors, in a group of kidney transplant recipients after a short period of personalized training programs with mixed exercises. In January 2013, at the Sports Medicine Center of the University of Florence, Italy, we began studying a group of 20 kidney transplant recipients. After 6 months of exercise, they underwent Cardiopulmonary Test (CPET), ECG, skin fold, bioimpedance analysis and stress test for the lower and upper limbs. EF increased significantly from 63.38 ± 4 to 67.30 ± 5.9 with p < 0.05; the anaerobic threshold improved from 14.48 ± 6.3 to 20.24 ± 3.7 (p < 0.05) with good stress tolerance, estimated by CR10 scale; weight decreased significantly (70.06–65.03 kg) as did skin folds at pectoral level (p < 0.002). Upper limb muscular strength increased significantly (p < 0.005). Regular mixed exercise is a proposed program in post-transplant syndrome with the expectation of improving cardiovascular performance and enhancing exercise tolerance. Muscle strength improves with physical fitness with consequent reduction of risk factors linked to visceral fat. Proof of an eventual positive impact on other complex aspects associated with post-transplant metabolic syndrome will require a longer follow-up.

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Acknowledgments

The authors wish to thank Dr. Alessandro Nanni Costa, Director of the “Centro Nazionale Trapianti, Roma” for giving them the opportunity to participate in the Multicenter National Protocol and Susan Seeley for her help with the English language.

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Authors and Affiliations

  1. Clinical and Experimental Department, Sports Medicine Center, University of Florence, Florence, Italy

    Giorgio Galanti, Laura Stefani, Gabriele Mascherini, Cristian Petri, Ilaria Corsani, Lorenzo Francini, Andrea Cattozzo & Marco Gianassi

  2. Division of Nephrology, University Hospital Careggi, Florence, Italy

    Enrico Minetti

  3. Organizzazione Toscana Trapianti (OTT), Tuscan Transplant Organization, Florence, Italy

    Alessandro Pacini

  4. Region of Tuscany, Directorate-General for the Rights of Citizenship and Social Cohesion, Florence, Italy

    Pier Giuseppe Calà

Authors
  1. Giorgio Galanti
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  2. Laura Stefani
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  3. Gabriele Mascherini
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  4. Cristian Petri
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  5. Ilaria Corsani
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  6. Lorenzo Francini
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  7. Andrea Cattozzo
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  8. Marco Gianassi
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  9. Enrico Minetti
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  10. Alessandro Pacini
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  11. Pier Giuseppe Calà
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Corresponding author

Correspondence to Laura Stefani.

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The authors declare that they have no conflict of interest.

Statement of human and animal rights

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This article does not contain any studies with human and animals performed by any of the authors.

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Informed consent was obtained from all individual participants included in the study.

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Galanti, G., Stefani, L., Mascherini, G. et al. Short-term prospective study of prescribed physical activity in kidney transplant recipients. Intern Emerg Med 11, 61–67 (2016). https://doi.org/10.1007/s11739-015-1294-5

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  • DOI: https://doi.org/10.1007/s11739-015-1294-5

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