Erratum to: Intern Emerg Med DOI 10.1007/s11739-009-0283-y
Unfortunately, the two sentences under the sections “Classification, structure, and regulation” (ninth paragraph: The activation of a pro-MMP is the…) and “MMPs and diabetes” (second paragraph: In fact, an upregulation of MMP-2 and -9 in the human…) in the present form are wrong. Please find the correct sentences here.
“The principal way for the activation of pro-MMPs is by the removal of its propeptide domain by tissue or plasmatic proteinases, including active MMPs. Moreover, pro-MMP activation can occur at the surface of cells, as in the case of MMP-2, or at intracellular level, as in the case of MMP-11, -21, -23, -27 and MT-MMPs.”
“In fact, an upregulation of MMP-2 and -9, which induce the expression of angiostatin, has been shown in the arterial vasculature of diabetics, suggesting that the enhanced production of angiostatin, a potent anti-angiogenic factor that antagonizes the expression and the activity of VEGF [61, 62], may explain the impaired angiogenesis of diabetes [63].”
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The online version of the original article can be found under doi:10.1007/s11739-009-0283-y.
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Busti, C., Falcinelli, E., Momi, S. et al. Matrix metalloproteinases and peripheral arterial disease. Intern Emerg Med 5, 89 (2010). https://doi.org/10.1007/s11739-009-0308-6
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DOI: https://doi.org/10.1007/s11739-009-0308-6