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Internal and Emergency Medicine

, Volume 3, Issue 2, pp 87–98 | Cite as

Optimizing management of metabolic syndrome to reduce risk: focus on life-style

  • Cristina Bianchi
  • Giuseppe Penno
  • Giuseppe Daniele
  • Luca Benzi
  • Stefano Del Prato
  • Roberto MiccoliEmail author
IM - Review

Abstract

The prevalence of metabolic syndrome (MS) is increasing all over the world and its incidence is expected to rise in the next years. Although genetic predisposition appears to play an important role in the regulation of metabolic parameters and in particular of body weight, the rapid increase in the prevalence of obesity and MS suggests that ecological factors (social, economic, cultural and physical environment) are promoting those conditions in susceptible individuals. People with MS are at increased risk of type 2 diabetes and cardiovascular disease and therefore they represent a priority target for preventive strategies. Life-style modifications based on healthy diet and increased physical activity are an effective preventing and therapeutic approach. Unfortunately, implementation of life-style modification and maintenance of effects is a difficult task both at personal and social level, thus drug therapy can be taken into account.

Keywords

Metabolic syndrome Life-style Insulin-resistance Type 2 diabetes Cardiovascular disease 

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Copyright information

© SIMI 2008

Authors and Affiliations

  • Cristina Bianchi
    • 1
  • Giuseppe Penno
    • 1
  • Giuseppe Daniele
    • 1
  • Luca Benzi
    • 1
  • Stefano Del Prato
    • 1
  • Roberto Miccoli
    • 1
    Email author
  1. 1.Department of Endocrinology and Metabolism, Section of Diabetes and MetabolismUniversity of PisaPisaItaly

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