Efficacy observation of acupuncture for dry eye syndrome of lung-yin deficiency pattern




To observe the clinical efficacy of combining two needling manipulations, Er Long Xi Zhu (two dragons playing with a pearl) and Guo Yan Re (heat produced to reach the eyes), in treating dry eye syndrome (DES) of lung-yin deficiency pattern.


Fifty-six eligible DES patients of lung-yin deficiency were randomized into an observation group and a control group, with 28 cases in each group. Same acupoints were selected in the two groups: Cuanzhu (BL 2), Sizhukong (TE 23), Taiyang (EX-HN 5) and Fengchi (GB 20) were chosen as the major points and Feishu (BL 13) and Chize (LU 5) as the adjuvant. Er Long Xi Zhu and Guo Yan Re needling manipulations were applied in the observation group while twirling reinforcing manipulation was used in the control group. Treatment was conducted once per day in both groups, for two sets of 15 consecutive days at a 2-day interval. Changes in the symptom score, tear break-up time (BUT) and tear production were observed afterwards, and the clinical efficacy was also compared between the two groups.


The total effective rate was 92.8% in the observation group, higher than 71.4% in the control group, and the between-group difference was statistically significant (P<0.05). After treatment, the symptom score, tear BUT and tear production showed significant improvements in both groups (all P<0.05); the symptom score, BUT and tear production in the observation group were significantly different from those in the control group (all P<0.05).


Given the same acupoint selection, combining Er Long Xi Zhu and Guo Yan Re needling manipulations can produce more significant clinical efficacy than twirling reinforcing manipulation in treating DES of lung-yin deficiency pattern.





将符合入组标准 的56例肺阴不足型干眼症患者随机分成观察组和对照组, 每组28例。两组取穴相同, 主穴取攒竹、丝竹空、太阳和 风池, 配穴取肺俞和尺泽。观察组采用“二龙戏珠”加“过眼热”针法, 对照组采用捻转补法。两组均每日治疗1次, 连续治疗15 d后休息2 d, 再治疗15 d后观察两组症状评分、泪膜破裂时间和泪液分泌量的变化, 并比较两组临床疗 效。


观察组总有效率为92.8%, 高于对照组的71.4%, 组间差异具有统计学意义(P<0.05)。治疗后, 两组症状评 分、泪膜破裂时间和泪液分泌量均较治疗前显著改善(均P<0.05); 观察组症状评分、泪膜破裂时间和泪液分泌量均 与对照组有统计学差异(均P<0.05)。


取穴相同的情况下, “二龙戏珠”结合“过眼热”针法治疗肺阴不足型 干眼症的临床疗效优于捻转补法。


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This work was supported by Project of Zheng’s Acupuncture Manipulation Academic School Heritage Studio, Gansu Province 甘肃郑氏针法学术流派传承工 作室建设项目, No. 9983999957).

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Correspondence to Zhao Yao-dong 赵耀东.

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Jing-wen, L., Yao-dong, Z., Ling, Z. et al. Efficacy observation of acupuncture for dry eye syndrome of lung-yin deficiency pattern. J. Acupunct. Tuina. Sci. 19, 72–77 (2021). https://doi.org/10.1007/s11726-021-1228-x

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  • Acupuncture Therapy
  • Acupuncture Reinforcing Method
  • Tear Break-up Time
  • Tear Secretion
  • Lung-yin Deficiency
  • Dry Eye Syndrome


  • 针刺疗法
  • 针刺补法
  • 泪膜破裂时间
  • 泪液分泌
  • 肺阴虚
  • 干眼症


  • R246.8


  • A