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Effect of combined acupuncture with Chinese medicine on overall function of patients with post-stroke depression

针药并用对脑卒中后抑郁症患者综合功能的影响

  • Clinical Study
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Journal of Acupuncture and Tuina Science Aims and scope Submit manuscript

摘要

目的

探讨针药并用对脑卒中后抑郁症(Post-stroke Depression, PSD)患者综合功能的影响。

方法

将128例PSD患者随机分为4组, 即中药组、 针刺组、 针药组、 西药组, 每组32 例。 分别在基础治疗基础上予中药、 针刺、 中药加针刺及氟西汀胶囊治疗。 治疗前后进行汉密尔顿抑郁量表(Hamilton Depression Rating Scale, HAMD)、 神经功能缺损程度(Neurological Impairment Severity, NIS)量表和功能综合评定量表(Functional Comprehensive Assessment, FCA)评定。

结果

与治疗前相比, 各组治疗后HAMD及NIS积分值均降低(P<0.01); FCA评分提高(P<0.01)。 组间治疗后比较, 针药组与其他3组积分差异有统计学意义(P<0.05或P<0.01), 中药组、 针刺组和西药组组间积分两两比较差异无统计学意义。

结论

各组治疗方案均能改善PSD患者抑郁症状和神经功能, 提高综合功能, 中药加针刺具有协同增效作用。

Abstract

Objective

To explore the effect of combined acupuncture with Chinese medicine on the overall function of patients with post-stroke depression (PSD).

Methods

A total of 128 cases were randomly allocated into 4 groups, namely, a Chinese medicine group, an acupuncture group, a combined acupuncture with Chinese medicine group and a Western medication group, 32 cases in each group. Other than routine treatment, patients in all 4 groups were respectively treated with Chinese medicine, acupuncture, combined acupuncture with Chinese medicine and Fluoxetine Capsule. Then the treatment effects were evaluated using Hamilton depression rating scale (HAMD), neurological impairment severity (NIS) and functional comprehensive assessment (FCA) before and after treatments.

Results

After treatment, both HAMD and NIS scores were decreased (P<0.01), whereas FCA scores were increased (P<0.01). Regarding the inter-group comparison, combined acupuncture with Chinese medicine group had statistical difference when compared with the other three groups (P<0.05 or P<0.01). There were no statistical differences among the Chinese medicine group, the acupuncture group and the Western medication group.

Conclusion

Each treatment protocol improves the depressive symptoms and neurological functions in PSD patients and enhances their overall function. Combined acupuncture with Chinese medicine can obtain a synergistic effect.

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Authors and Affiliations

  1. Tianshan Hospital of Traditional Chinese Medicine, Changning District, Shanghai, Shanghai, 200051, P. R. China

    Cui-xia Zhou  (周翠侠), Xiao Cui  (崔晓), Hui-ling Zeng  (曾慧玲), Huan-huan Ni  (倪欢欢), Chun-shui Huang  (黄春水), Ji Wu  (吴佶), Jun-chao Shi  (史骏超) & Mei-lan Feng  (冯美兰)

  2. Department of Rehabilitation Medicine, Huashan Hospital Affiliated to Fudan University, Shanghai, 200040, P. R. China

    Yong-shan Hu  (胡永善)

Authors
  1. Cui-xia Zhou  (周翠侠)
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  2. Xiao Cui  (崔晓)
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  3. Yong-shan Hu  (胡永善)
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  4. Hui-ling Zeng  (曾慧玲)
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  5. Huan-huan Ni  (倪欢欢)
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  6. Chun-shui Huang  (黄春水)
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  7. Ji Wu  (吴佶)
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  8. Jun-chao Shi  (史骏超)
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  9. Mei-lan Feng  (冯美兰)
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Corresponding author

Correspondence to Cui-xia Zhou  (周翠侠).

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Zhou, Cx., Cui, X., Hu, Ys. et al. Effect of combined acupuncture with Chinese medicine on overall function of patients with post-stroke depression. J. Acupunct. Tuina. Sci. 10, 99–103 (2012). https://doi.org/10.1007/s11726-012-0581-1

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  • DOI: https://doi.org/10.1007/s11726-012-0581-1

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