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Preliminary study of biodegradation of AZ31B magnesium alloy

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Abstract

Magnesium alloys are potential to be developed as a new type of biodegradable implant material by use of their active corrosion behavior. Both in vitro and in vivo biodegradation properties of an AZ31B magnesium alloy were investigated in this work. The results showed that AZ31B alloy has a proper degradation rate and much lower hydrogen release in Hank’s solution, with a degradation rate of about 0.3 mm/year and hydrogen release below 0.15 mL/cm2. The animal implantation test showed that the AZ31B alloy could slowly biodegrade in femur of the rabbit and form calcium phosphate around the alloy sample, with the Ca/P ratio close to the natural bone.

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References

  1. Staiger M P, Pietak A M, Huadmai J, et al. Magnesium and its alloys as orthopedic biomaterials: A review. Biomaterials, 2006, 27(9): 1728–1734

    Article  CAS  Google Scholar 

  2. Stroganov G B, Savitsky E, Mikhailovich T, et al. Magnesium-base alloy for use in bone surgery. US Patent, 3 687 135, 1972

  3. McBride E D. Absorbable metal in bone surgery. JAMA, 1938, 111(27): 2464–2467

    CAS  Google Scholar 

  4. Witte F, Kaese V, Haferkamp H, et al. In vivo corrosion of four magnesium alloys and the associated bone response. Biomaterials, 2005, 26(17): 3357–3563

    Google Scholar 

  5. Mario C D, Griffiths H, Goktekin O, et al. Drug-eluting bioabsorbable magnesium stent. Journal of Interventional Cardiology, 2004, 17(6): 391–395

    Article  Google Scholar 

  6. Heublein B, Rohde R, Kaese V, et al. Biocorrosion of magnesium alloys: A new principle in cardiovascular implant technology? Heart, 2003, 89: 651–656

    Article  CAS  Google Scholar 

  7. Ren Y B, Huang J J, Yang K, et al. Study of bio-corrosion of pure magnesium. Acta Metallurgica Sinica, 2005, 41(11): 1228–1232 (in Chinese)

    CAS  Google Scholar 

  8. Ren Y B, Wang H, Huang J J, et al. Study of biodegradation of pure magnesium. Key Engineering Materials, 2007, 342–343: 601–604

    Article  Google Scholar 

  9. Kuwahara H, Al-Abdullat Y, Mazaki N, et al. Precipitation of magnesium apatite on pure magnesium surface during immersing in Hank’s solution. Materials Transactions, 2001, 42(7): 1317–1321

    Article  CAS  Google Scholar 

  10. Pu S Y. Metal Implantable Materials and Its Corrosion. Beijing: Beijing University of Aeronautics and Astronautics Press, 1990 (in Chinese)

    Google Scholar 

  11. Yu Y T, Zhang X D. Biomedical Materials. Tianjin: Tianjin University Press, 2000 (in Chinese)

    Google Scholar 

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Authors and Affiliations

  1. Institute of Metal Research, Chinese Academy of Sciences, Shenyang, 110016, China

    Ren Yibin, Huang Jingjing, Zhang Bingchun & Yang Ke

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  1. Ren Yibin
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  2. Huang Jingjing
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  3. Zhang Bingchun
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  4. Yang Ke
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Correspondence to Ren Yibin.

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Ren, Y., Huang, J., Zhang, B. et al. Preliminary study of biodegradation of AZ31B magnesium alloy. Front. Mater. Sci. China 1, 401–404 (2007). https://doi.org/10.1007/s11706-007-0073-2

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  • DOI: https://doi.org/10.1007/s11706-007-0073-2

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