Abstract
Clinical practice has drastically changed following the 2014 U.S. Food and Drug Administration (FDA) warning statement regarding power morcellation during laparoscopic hysterectomy and myomectomy. Despite investigation into alternative tissue extraction techniques, there remain a paucity of data associated with contained manual morcellation techniques. The goal of this study was to investigate the associated perioperative outcomes of contained manual morcellation compared to power morcellation in women undergoing robotic myomectomy. Performing manual morcellation (n = 38) resulted in a 21-min decrease in mean operative time (105.4 ± 42.2 vs 126.1 ± 44.1 min, p = 0.02) compared to power morcellation (n = 62). Women were younger (33 vs 36 years, p = 0.03) in the manual morcellation group, with all other patient demographics being similar. Median specimen weight (82 vs 104 g, p = 0.13), number of fibroids removed (2 vs 1, p = 0.16), estimated blood loss (10 vs 50 mL, p = 0.25), and post-operative morphine equivalents administered (5.57 ± 4.57 vs 5.29 ± 4.39, p = 0.76) were similar. The same-day discharge rate was not significantly different between the groups (86 vs 90%, p = 0.74). Linear regression modeling identified specimen weight, number of fibroids removed, and use of power morcellation as significant contributors to surgical time. Contained manual morcellation during robotic myomectomy is associated with a significant decrease in surgical time when compared to power morcellation, with similar post-operative narcotic administration and length of stay.
Similar content being viewed by others
References
Steiner FA, Wight E, Tadir Y, Haller U (1993) Electrical cutting device for laparoscopic removal of tissue from the abdominal cavity. Obstet Gynecol 81:471–474
Carter JE, McCarus SD (1997) Laparoscopic myomectomy: time and cost analysis of power vs. manual morcellation. J Reprod Med 42:383–388
Moore M, Brown T, Cohen M (2004) Complications of laparoscopic morcellation. J Am Assoc Gynecol Laparosc 11:S80
Kho KA, Nezhat CH (2014) Evaluating risks of electric uterine morcellation. JAMA 311(9):905–906
U.S. Food and Drug Administration (2014) Laparoscopic uterine power morcellator in hysterectomy and myomectomy: FDA Safety Communication, issued 17 Apr 2014. http://www.fda.gov/MedicalDevices/Safety/AlertsandNotices/ucm393576.htm. Accessed 12 Feb 2017
Lum DA, Sokol ER, Berek JS, Schulkin J, Chen L, McElwain CA, Wright JD (2016) Impact of 2014 Food and Drug Administration warnings against power morcellation. J Minim Invasive Gynecol 23(4):548–556
Barron KI, Richard T, Robinson TS, Lamvu G (2015) Association of the U.S. Food and Drug Administration morcellation warning with rates of minimally invasive hysterectomy and myomectomy. Obstet Gynecol 126(6):1174–1180
Harris JA, Swenson CW, Uppal S, Kamdar N, Mahnert N, As-Sanie S, Morgan DM (2016) Practice patterns and postoperative complications before and after US Food and Drug Administration safety communication on power morcellation. Am J Obstet Gynecol 214(1):98.e1–98.e13
Po L, Lee PE (2016) The unintended consequences of an FDA warning: the case of power morcellation in myoma surgery. J Minim Invasive Gynecol 23(4):597–602
Einarsson JI, Cohen SL, Fuchs N, Wang KC (2014) In-bag morcellation. J Minim Ivasive Gynecol 21(5):951–953
Paul PG, Thomas M, Das T, Patil S, Garg R (2015) Contained morcellation for laparoscopic myomectomy within a specially designed bag. J Minim Invasive Gyncol 23(2):257–260
Troung MD, Advincula AP (2014) The extracorporeal c-incision tissue extraction (ExCITE) technique. OBG Manag 26(11):56
Kho KA, Brown DN (2016) Surgical treatment of uterine fibroids within a containment system and without power morcellation. Clin Obstet Gynecol 59(1):85–92
Frasca C, Degli Esposti E, Arena A, Tuzzato G, Moro E, Martelli V, Seracchioli R (2018) Can in-bag manual morcellation represent an alternative to uncontained power morcellation in laparoscopic myomectomy? A randomized controlled trial. Gynecol Obstet Invest 83:52–56
Venturella R, Rocca ML, Lico D, La Ferrera N, Cirillo R, Gizzo S, Morelli M, Zupi E, Zullo F (2016) In-bag manual versus uncontained power morcellation for laparoscopic myomectomy: randomized controlled trial. Fertil Steril 105(5):1369–1376
Sanderson D, Sanderson R, Ghomi A (2016) Robot-assisted laparoscopic myomectomy: a comparison of techniques. J Gynecol Surg 32(6):329–334
R Core Team (2015) R: a language environment for statistical computing. Version 3.2.3. R Foundation for Statistical Computing, Vienna. https://www.r-projection.org/
RStudio Team (2015) RStudio: integrated development for R. RStudio, Inc., Boston. http://www.rstudio.com/
Canty A, Ripley B (2015) boot: Bootstrap R (S-Plus) functions. R package Version 1:3-17
Davison AC, Hinkley DV (1997) Bootstrap methods and their applications. Cambridge University Press, Cambridge (ISBN 0-521-57391-2)
Ruxton GD (2006) The unequal variance t-test is an underused alternative to Student’s t-test and the Mann–Whitney U test. Behav Ecol 17(4):688–690
Gaddis GM, Gaddis ML (1990) Introductions to biostatics: part 5, statistical inference techniques for hypothesis testing with nonparametric data. Ann Emerg Med 19(9):1054–1059
Dubin AK, Wei JW, Sullivan S, Udaltsova N, Zaritsky E, Yamamoto MP (2017) Minilaparotomy versus laparoscopic myomectomy after cessation of power morcellation: rate of wound complications. JMIG 24(6):946–953
Alton K, Sullivan S, Udaltsova N, Yamamoto M, Zaritsky E (2016) Same-day discharge after minimally invasive myomectomy. Obstet Gynecol 127:539–544
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
The authors Derrick J Sanderson, Rohnn Sanderson, Dana Cleason, Catherine Seaman, and Ali Ghomi declare that they have no conflicts of interest.
Rights and permissions
About this article
Cite this article
Sanderson, D.J., Sanderson, R., Cleason, D. et al. Manual morcellation compared to power morcellation during robotic myomectomy. J Robotic Surg 13, 209–214 (2019). https://doi.org/10.1007/s11701-018-0837-y
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11701-018-0837-y