Obesity Surgery

, Volume 28, Issue 4, pp 916–922 | Cite as

Prevalence and Predictors of Gastroesophageal Reflux Disease After Laparoscopic Sleeve Gastrectomy

  • Saad Althuwaini
  • Fahad Bamehriz
  • Abdullah Aldohayan
  • Waleed Alshammari
  • Saleh Alhaidar
  • Mazen Alotaibi
  • Abdullah Alanazi
  • Hossam Alsahabi
  • Majid Abdularahman Almadi
Original Contributions


Background and Aims

Laparoscopic sleeve gastrectomy (LSG) might be associated with a new onset or worsening of gastroesophageal reflux disease (GERD). We aim to evaluate the prevalence of post-LSG GERD symptoms and its predictors.


We included patients who underwent primary LSG at a university hospital from 2009 to 2015. We used the GERD-Health-Related Quality of Life (GERD-HRQL) questionnaire and included questions regarding regurgitation to evaluate symptoms before and after LSG; each item was scored from 1 to 5 based on the symptom severity.


A total of 213 patients (mean age, 36.08 ± 10.22 years; 48.36% were men) were included. The mean preoperative body mass index (BMI) was 47.84 kg/m2, mean percent total weight loss was 37.99% (95% CI, 36.64 to 39.34), mean percent excess weight loss was 84.14% (95% CI, 80.91 to 87.36), and the mean percent excess BMI loss was 84.17% (95% CI, 80.94 to 87.41). The mean heartburn score while standing increased (0.71 vs. 1.09, p < 0.01) as well as the score of heartburn requiring a diet change (0.67 vs. 1.16, p < 0.01) post-LSG. The scores for dysphagia, odynophagia, and regurgitation increased. New-onset heartburn was reported in 47.06% of our cohort. Those with high preoperative BMIs were less likely to develop new-onset or worsening symptoms of GERD (odds ratio [OR], 0.97; 95% confidence interval [CI], 0.95–0.99). More severe heartburn symptoms while standing were associated with higher risks of developing or worsening GERD symptoms (OR, 1.22; 95% CI, 1.01–1.47). None of the other variables could predict the development or worsening of the GERD symptoms.


Symptoms of heartburn and regurgitation are common after LSG; however, none of the variables preoperatively could strongly predict patients who would develop new onset or experience worsening of symptoms postoperatively.


Bariatric surgery Gastroesophageal reflux Heartburn Laparoscopic sleeve gastrectomy GERD-HRQL 



The authors extend their sincere appreciation to the Deanship of Scientific Research at King Saud University for funding this research through the Research Group Project number RGP-279.

Author Contributions

Majid A Almadi: analysis of the data; writing, drafting, and revising of the manuscript for important intellectual content; and final approval of the version to be published

Saad Althuwaini, Fahad Bamihriz, Abdullah Aldohayen, Waleed Alshammari, Saleh Alhaidar, Mazen Alotaibi, Abdullah Alanazi, Hossam Alsahabi: acquisition of data, revising of the manuscript critically for important intellectual content, and final approval of the version to be published

Compliance with Ethical Standards

Conflict of interest

The authors declare that they have no conflict of interest.


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Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  • Saad Althuwaini
    • 1
  • Fahad Bamehriz
    • 1
  • Abdullah Aldohayan
    • 1
  • Waleed Alshammari
    • 1
  • Saleh Alhaidar
    • 1
  • Mazen Alotaibi
    • 1
  • Abdullah Alanazi
    • 1
  • Hossam Alsahabi
    • 1
  • Majid Abdularahman Almadi
    • 2
    • 3
  1. 1.Surgery DivisionKing Khalid University Hospital, King Saud UniversityRiyadhSaudi Arabia
  2. 2.Gastroenterology DivisionKing Khalid University Hospital, King Saud UniversityRiyadhSaudi Arabia
  3. 3.Gastroenterology Division, McGill University Health CenterMontreal General Hospital, McGill UniversityMontrealCanada

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