Obesity Surgery

, Volume 28, Issue 4, pp 996–1001 | Cite as

Comparison of Short-Term Effectiveness and Postoperative Complications: Laparoscopic Gastric Plication vs Laparoscopic Sleeve Gastrectomy

  • Mohammad Talebpour
  • Donya Sadid
  • Atieh Talebpour
  • Amirsina Sharifi
  • Farzad Vaghef Davari
Original Contributions



Bariatric surgeries are the only effective long-term treatment in obese patients. The innovation of laparoscopic gastric plication (LGP) raised some questions about its effectiveness compared to traditionally used techniques such as laparoscopic sleeve gastrectomy (LSG). We tried to answer some of these questions.

Materials and Methods

We investigated 70 patients in a randomized clinical trial (IRCT2013123012294N5) from 2012 to 2015. Thirty-five patients were randomly assigned to each LSG or LGP group, using sealed envelope method. The body mass index (BMI) reduction and the percentage of excess weight loss (%EWL) along with %total body weight loss (%TWL) were primary endpoint and were assessed at follow-up periods. We recorded postoperative complications, as well.


Two-year follow-up rate was 100%. There were no statistically significant differences between the two groups in means of preoperative BMI. Also, postoperative follow-ups were not suggestive for a significant difference in BMI (all p values > 0.05). The mean %EWL at follow-ups showed no significant difference at any point, except for 3 and 6 months after surgery (p value = 0.002 and 0.017, respectively). This finding was confirmed by %TWL trend in 12 months after surgery. LSG patients were readmitted more than LGP patients (seven cases vs one case, p value = 0.024). Postoperative complications such as nausea and vomiting, hair loss, iron deficiency, vitamin D deficiency, and cholelithiasis were not different between the two groups. There was one death in the LGP group due to pulmonary thromboembolism.


LGP showed to be efficient regarding %EWL and %TWL reduction in short-term follow-ups with comparable postoperative complications to LSG.


Laparoscopic sleeve gastrectomy Laparoscopic gastric plication Short-term follow-up Excess weight loss Postoperative complication 



The authors would like to thank research development center of Sina Hospital and primary prevention of cardiovascular disease research center for their kind contributions in every step of performing this study.

Compliance with Ethical Standards

Conflict of Interest

All authors declare that they have no conflict of interest.

Statement of Informed Consent

Informed consent was obtained from all the patients participated in the study (General note#2).

Statement of Human and Animal Rights/Ethical Approval

The institutional review board and the ethic committee of Tehran University of Medical Sciences approved the study protocol for Human rights (General note#2).


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Copyright information

© Springer Science+Business Media, LLC 2017

Authors and Affiliations

  1. 1.Sina Trauma and Surgery Research CenterTehran University of Medical SciencesTehranIran
  2. 2.Hasan Abad Square, Sina HospitalTehranIran

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