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Weight Loss After Gastric Banding is Associated with Pouch Pressure and not Pouch Emptying Rate

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Abstract

Background

Morbid obesity defined as BMI > 40 is a growing problem. It is primarily treated with diet, lifestyle changes, and medicine. However, at present, surgery remains the only effective option for the management.

Methods

Seventeen patients were studied 2 months after laparoscopic gastric banding. The aims were to evaluate the association between (1) the extent of pouch filling and satiety, (2) gastric emptying and weight loss, and (3) the pouch pressure during a meal and the sensation of satiety and weight loss.

Results

The preoperative weight was 146 kg (range 108–202 kg). The average weight loss was 21 kg between the banding and the examination. The half time (T 50%) for the pouch emptying was 3 min (quartiles 3–12.5) and the time to 90% of pouch emptying (T 90%) was 40 min (24.5–60). The sensation of satiety lasted 75 min (57.5–105), and the feeling of hunger started after 90 min (40–90). Neither T 50% nor T 90% correlated to the weight loss (R = 0.006, P > 0.5 and R = 0.1, P > 0.5). The sensation of satiety did not correlate to T 50% or T 90% (R = 0.6, P = 0.12 and R = 0.5, P = 0.15). No association was found between the sensory data and the pressure decline. Significant association was found between the load of the meal expressed as the area under the pouch pressure curve and the weight loss (R = 0.786, P = 0.015).

Conclusion

The satiety sensation lasted much longer than the pouch emptying and the pressure increase. The pressure load correlated to the weight loss. This indicates that neuroendocrine mechanisms caused by the accumulated mechanical load are most important for maintaining satiety.

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Disclosure

There is no any commercial interest in the subject of study and the source of any financial or material support.

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Author notes

  1. Hans Gregersen

    Present address: Aalborg Hospital Science and Innovation Center, Sdr. Skovvej 15, DK-9100, Aalborg, Denmark

Authors and Affiliations

  1. Mech-Sense, Aalborg Hospital Science and Innovation Center, Sdr. Skovvej 15, DK-9100, Aalborg, Denmark

    Jan Bech Pedersen, Asbjørn Mohr Drewes & Hans Gregersen

  2. Surgical Gastroenterology, Aarborg Hospital, Aarhus University Hospital, Aalborg, Denmark

    Jan Bech Pedersen, Jens Fromholt Larsen & Hans Gregersen

  3. Gastroenterology, Aarborg Hospital, Aarhus University Hospital, Aalborg, Denmark

    Asbjørn Mohr Drewes

  4. Clinical Physiology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark

    Anne Arveschoug

  5. Endocrinology, Aalborg Hospital, Aarhus University Hospital, Aalborg, Denmark

    Jens Peter Kroustrup

Authors
  1. Jan Bech Pedersen
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  2. Jens Fromholt Larsen
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  3. Asbjørn Mohr Drewes
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  4. Anne Arveschoug
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  5. Jens Peter Kroustrup
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  6. Hans Gregersen
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Corresponding author

Correspondence to Hans Gregersen.

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Pedersen, J.B., Larsen, J.F., Drewes, A.M. et al. Weight Loss After Gastric Banding is Associated with Pouch Pressure and not Pouch Emptying Rate. OBES SURG 19, 850–855 (2009). https://doi.org/10.1007/s11695-009-9832-8

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  • DOI: https://doi.org/10.1007/s11695-009-9832-8

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