Frontiers of Medicine

, Volume 11, Issue 2, pp 277–283 | Cite as

Preliminary clinical study on non-transecting anastomotic bulbomembranous urethroplasty

  • Wei Le
  • Chao Li
  • Jinfu Zhang
  • Denglong Wu
  • Bo Liu
Research Article


This study aims to investigate the effect of non-transecting anastomotic urethroplasty for treatment of posterior urethral stricture. A total of 23 patients with traumatic posterior urethral stricture were enrolled and then divided into two groups. In one group, 12 patients underwent non-transecting anastomotic urethroplasty. In the other group, 11 patients underwent conventional posterior urethra end-to-end anastomosis. The effect of operation was evaluated using the following parameters: the bleeding amount during operation, operation time, IIEF-5 scores after operation, maximum flow rate (Qmax), and rating scale of quality of life (QoL). The comparison between the conventional posterior urethra end-to-end anastomosis group and the non-transecting anastomotic urethroplasty group showed no significant difference with regard to average operation time. However, a significant difference was observed between the groups with regard to the bleeding amount during operation. The patients in the group of non-transecting anastomotic urethroplasty urinated smoothly after the removal of catheter. Meanwhile, one patient from the group of conventional posterior urethra end-to-end anastomosis had difficulty urinating after the removal of catheter. Furthermore, significant differences in the operation time, bleeding amount during operation, IIEF-5 scores after operation, and rating scale of QoL were observed, whereas no significant difference was observed between urine flow rates of the two groups after operation. Overall, nontransecting anastomotic urethroplasty is effective for posterior urethra reconstruction, and it can reduce the occurrence rate of erectile dysfunction after operation.


anastomotic urethroplasty transecting posterior urethra reconstruction 


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This work was supported by the National Natural Science Foundation of China (No.81370793). We are very grateful to Prof. Yuemin Xu for his guidance in the design of this study, the operation part, and the provision of some patients’ follow-up data.


  1. 1.
    Hampson LA, McAninch JW, Breyer BN. Male urethral strictures and their management. Nat Rev Urol 2014; 11(1): 43–50CrossRefPubMedGoogle Scholar
  2. 2.
    Lumen N, Hoebeke P, Willemsen P, De Troyer B, Pieters R, Oosterlinck W. Etiology of urethral stricture disease in the 21st century. J Urol 2009; 182(3): 983–987CrossRefPubMedGoogle Scholar
  3. 3.
    Sangkum P, Levy J, Yafi FA, Hellstrom WJ. Erectile dysfunction in urethral stricture and pelvic fracture urethral injury patients: diagnosis, treatment, and outcomes. Andrology 2015; 3(3): 443–449CrossRefPubMedGoogle Scholar
  4. 4.
    Shenfeld OZ, Kiselgorf D, Gofrit ON, Verstandig AG, Landau EH, Pode D, Jordan GH, McAninch JW. The incidence and causes of erectile dysfunction after pelvic fractures associated with posterior urethral disruption. J Urol 2003; 169(6): 2173–2176CrossRefPubMedGoogle Scholar
  5. 5.
    Tang CY, Fu Q, Cui RJ, Sun XJ. Erectile dysfunction in patients with traumatic urethral strictures treated with anastomotic urethroplasty: a single-factor analysis. Can J Urol 2012; 19(6): 6548–6553PubMedGoogle Scholar
  6. 6.
    Fu Q, Zhang J, Sa YL, Jin SB, Xu YM. Recurrence and complications after transperineal bulboprostatic anastomosis for posterior urethral strictures resulting from pelvic fracture: a retrospective study from a urethral referral centre. BJU Int 2013; 112(4): E358–E363CrossRefPubMedGoogle Scholar
  7. 7.
    de Groat WC, Yoshimura N. Anatomy and physiology of the lower urinary tract. Handbook of Clinical Neurology 2015; 130: 61–108CrossRefPubMedGoogle Scholar
  8. 8.
    Clement P, Giuliano F. Anatomy and physiology of genital organs — men. Handbook of Clinical Neurology 2015; 130: 19–37CrossRefPubMedGoogle Scholar
  9. 9.
    Andrich DE, Mundy AR. Non-transecting anastomotic bulbar urethroplasty: a preliminary report. BJU Int 2012; 109(7): 1090–1094CrossRefPubMedGoogle Scholar
  10. 10.
    Feng C, Xu YM, Barbagli G, Lazzeri M, Tang CY, Fu Q, Sa YL. The relationship between erectile dysfunction and open urethroplasty: a systematic review and meta-analysis. J Sex Med 2013; 10 (8): 2060–2068CrossRefPubMedGoogle Scholar
  11. 11.
    Feng C, Xu YM, Yu JJ, Fei XF, Chen L. Risk factors for erectile dysfunction in patients with urethral strictures secondary to blunt trauma. J Sex Med 2008; 5(11): 2656–2661CrossRefPubMedGoogle Scholar

Copyright information

© Higher Education Press and Springer-Verlag Berlin Heidelberg 2017

Authors and Affiliations

  • Wei Le
    • 1
    • 2
  • Chao Li
    • 1
  • Jinfu Zhang
    • 3
  • Denglong Wu
    • 1
  • Bo Liu
    • 1
  1. 1.Department of Urology, Tongji HospitalTongji University School of MedicineShanghaiChina
  2. 2.Department of Reproduction and Andrology, Tongji HospitalTongji University School of MedicineShanghaiChina
  3. 3.Department of Reproduction and AndrologyTongren Hospital Affiliated to Shanghai Jiao Tong UniversityShanghaiChina

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