Skip to main content
Log in

Differential diagnosis of Warthin’s tumor complicated with lung adenocarcinoma by 18F- FDG PET/CT imaging and radioisotope scanning with Tc-99m pertechnetate: A case report and literature review

  • Case Report
  • Published:
Chinese Journal of Cancer Research

Abstract

A seventy eight years old male patient underwent a whole body 18F- FDG PET/CT imaging to diagnose the lesion which was showed in the right lung by a chest X ray test and CT scan before. Besides the intense 18F- FDG uptake of the lesion in the right lung, a lesion in the left parotid gland also showed intense 18F- FDG uptake. To evaluate the pathology of the lesion in the left parotid gland, a parotid gland scintigraphy imaging with Tc-99m pertechnetate was done and revealed a Warthin’s tumor. Later a fine needle aspiration(FNA) confirmed that it was a Warthin’s tumor.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

References

  1. Rice DH. Salivary Gland Disorders: neoplastic and nonneoplastic[J]. Med Clin North Am 1999; 83: 197–218.

    Article  CAS  PubMed  Google Scholar 

  2. Saxena A, Memauri B, Hasegawa W. Initial diagnosis of small lymphocytic lymphoma in parotidectomy for Wathin tumour, a rare collision tumour[J]. J Clin Pathol 2005; 58: 331–333.

    Article  CAS  PubMed  Google Scholar 

  3. Weinstein GS, Harvey RT, Zimmer W, et al. Technetium-99m pertechnetate salivary gland imaging: its role in the diagnosis of Warthin’s tumor [J]. J Nucl Med 1994; 35: 179–183.

    CAS  PubMed  Google Scholar 

  4. Lamelas J, Terry JH, Alfonso AE. Warthin’s tumor: multicentricity and increasing incidence in women[J]. Am J Surg 1987; 154: 347–351.

    Article  CAS  PubMed  Google Scholar 

  5. Higashi T, Murahashi H, Iluta H, et al. Identification of Warthin’s tumor with technetium-99m pertechnetate[ J]. Clin Nucl Med 1987; 12: 796–800.

    Article  CAS  PubMed  Google Scholar 

  6. Batsakis JG. Carcinoma ex papillary cystadenoma lymphomatosum malignant Warthin’s tumor[J]. Ann Otol Rhinol laryngol 1987; 96: 234–235.

    CAS  PubMed  Google Scholar 

  7. Finkelstein DM, Noyek AM, Chapnik JS. Multiple bilateral synchronous Warthin’s tumors: a case report and review of the literature[J]. J Otolaryngol 1989; 18: 357–361.

    CAS  PubMed  Google Scholar 

  8. Nishiyama Y. The mechanism of positive scintigraphy with 99m Tc-pertechnetate in adenolymphomas of the parotid grand[J]. Nippon Jibiinkoka Gakkai Kaiho(in Japanese) 1998; 101: 615–619.

    CAS  Google Scholar 

  9. Uchida Y, Minoshima S, Kawata T, et al. Diagnostic value of FDG PET and salivary gland scintigraphy for parotid tumors[J]. Clin Nucl Med 2005; 30: 170–176.

    Article  PubMed  Google Scholar 

  10. Sostre S, Medina L, de Arellano GR. The various scintigraphic patterns of Warthin’s tumor[J]. Clin Nuc Med 1987; 12: 620–626.

    Article  CAS  Google Scholar 

  11. Metser U, Miller E, Lerman H, et al. Benign nonphysiologic lesions with increased 18F- FDG uptake on PET/CT: characterization and incidence[J]. AJR Am J Roentgenol 2007; 189:1203–1210.

    Article  PubMed  Google Scholar 

  12. Ozawa N, Okamura T, Koyama K, et al. Retrospective review: usefulness of a number of imaging modalities including CT, MRI, technetium-99m pertechnetate scintigraphy, gallium-67 scintigraphy and F-18-FDG PET in the differentiation of benign from malignant parotid masses[J]. Radiat Med 2006; 24: 41–49.

    Article  PubMed  Google Scholar 

  13. Basu S, Houseni M, Alavi A. Significance of incidental fluorodeoxyglucose uptake in the parotid glands and its impact on patient management[J]. Nucl Med Commun 2008; 29: 367–373.

    Article  CAS  PubMed  Google Scholar 

  14. Horiuchi M, Yasuda S, Shohtsu A, et al. Four cases of Warthin’s tumor of the parotid gland detected with FDG PET[J]. Ann Nucl Med 1998; 12: 47–50.

    Article  CAS  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Jia-rui Zhu.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Fang, Tz., Zhu, Jr., Chuan, L. et al. Differential diagnosis of Warthin’s tumor complicated with lung adenocarcinoma by 18F- FDG PET/CT imaging and radioisotope scanning with Tc-99m pertechnetate: A case report and literature review. Chin. J. Cancer Res. 22, 163–166 (2010). https://doi.org/10.1007/s11670-010-0163-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11670-010-0163-z

Key words

CLC number

Navigation