Intestinal Microbiota and Kidney Diseases

Feature article

Abstract

Kidney diseases are common and the incidence rate is increasing. Gut microbiota is involved in metabolic and immune regulation of the host. Genetic, alimentary and environmental disease factors may change gut flora and increase opportunistic and pathogenic bacteria, contributing to immune or non-immune mediated kidney diseases including IgA nephropathy and diabetic nephropathy. Additionally, bacterial metabolites may be a source of uremic toxins. Thus, identififi cation of diversity, composition, and metabolic and immunologic features of gut bacteria in chronic kidney diseases may help understand pathogenetic mechanism and develop therapy for diseases.

Keywords

microbiota IgA nephropathy chronic kidney disease uremia 

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Notes

Acknowledgments

We sincerely thank Zheng ZH for his critical review and editing of the manuscript.

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Copyright information

© Chinese Association of the Integration of Traditional and Western Medicine 2017

Authors and Affiliations

  1. 1.Advanced Institute for Medical Science, The Second HosptialDalian Medical UniversityDalian, Liaoning ProvinceChina

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