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Comparison of Long-term Quality of Life in Patients with Esophageal Cancer after Ivor-Lewis, Mckeown, or Sweet Esophagectomy

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Journal of Gastrointestinal Surgery Aims and scope

Abstract

Background

The aim of this study was to compare the long-term quality of life (QoL) in patients after Sweet, Ivor-Lewis, or Mckeown esophagectomy.

Methods

Esophageal cancer patients after Sweet, Ivor-Lewis, or Mckeown esophagectomy from 2010 to 2012 were included. QoL was assessed according to the European Organization for Research and Treatment of Cancer general questionnaire: QLQ-C30 and esophagus-specific questionnaire: QLQ-OES18.

Results

A total of 126 qualified patients who have been alive for more than 3 years without tumor recurrence were divided into three groups: the Sweet group (n = 40), Ivor-Lewis group (n = 38), and Mckeown group (n = 48). Among these three groups, the QLQ-C30 mean scores of global health status, functional and symptom scales, and general QoL were similar. The symptom scales of QLQ-OSE18 showed that patients who had a Mckeown operation experienced more problem of eating (P = 0.029), choking when swallowing (P = 0.010) and coughing (P = 0.016), while patients undergoing Sweet operation complained more symptom of reflux (P = 0.003) and pain (P = 0.000).

Conclusions

All three types of esophagectomy provided a generally good long-term QoL. However, patients in Sweet and Mckeown group tend to suffer from a higher symptomatic burden as compared to Ivor-Lewis approach.

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Author notes

  1. Yu-Shang Yang and Qi-Xin Shang contributed equally to this work.

Authors and Affiliations

  1. Department of Thoracic Surgery, West China Hospital of Sichuan University, No. 37, Guoxue Alley, Chengdu, 610041, Sichuan, China

    Yu-Shang Yang, Qi-Xin Shang, Yong Yuan, Xiao-Ying Wu, Wei-Peng Hu & Long-Qi Chen

Authors
  1. Yu-Shang Yang
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  2. Qi-Xin Shang
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  3. Yong Yuan
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  4. Xiao-Ying Wu
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  5. Wei-Peng Hu
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Contributions

(I) Conception and design: Long-Qi Chen, Yu-Shang Yang, and Yong Yuan;

(II) Administrative support: Wei-Peng Hu and Yu-Shang Yang;

(III) Provision of study materials or patients: Qi-Xin Shang and Yu-Shang Yang;

(IV) Collection and assembly of data: Yu-Shang Yang, Xiao-Ying Wu, and Qi-Xin Shang;

(V) Data analysis and interpretation: Qi-Xin Shang, Wei-Peng Hu, and Yong Yuan;

(VI) Manuscript writing: All authors;

(VII) Final approval of manuscript: All authors.

Corresponding author

Correspondence to Yong Yuan.

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The authors declare that they have no competing interests.

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Yang, YS., Shang, QX., Yuan, Y. et al. Comparison of Long-term Quality of Life in Patients with Esophageal Cancer after Ivor-Lewis, Mckeown, or Sweet Esophagectomy. J Gastrointest Surg 23, 225–231 (2019). https://doi.org/10.1007/s11605-018-3999-z

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  • DOI: https://doi.org/10.1007/s11605-018-3999-z

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