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Evaluation of coronary artery variations using dual-source coronary computed tomography angiography in neonates with transposition of the great arteries

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Abstract

Objective

The purpose of this study was to investigate whether the origins and courses of the coronary arteries could be better assessed using ECG-gated dual-source computed tomography (CT) than with echocardiography in neonates with transposition of the great arteries (TGA).

Methods

A total of 17 neonates within 14 days old who underwent both echocardiography and retrospective ECG-gated coronary CT angiography were retrospectively reviewed. The patients were sedated and intubated during CT examinations, and CT images were obtained with a breath-hold. CT images were reconstructed by multiple cardiac phases, and the coronary artery assessment was performed in the most static phase. Coronary anomalies were classified by Shaher’s classification and validated by surgical findings.

Results

CT correctly classified 16 of 17 cases (Shaher type 1: 7, type 2: 4, type 9: 3, type 3: 1, type 4: 2), whereas echocardiography classified only 8 of 17 cases correctly. Dual-source CT had a significantly higher diagnostic ability than echocardiography (p = 0.0078).

Conclusion

Dual-source coronary CT angiography has a higher diagnostic ability than echocardiography in the assessment of the origins and courses of the coronary arteries in neonates with TGA.

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Abbreviations

ECG:

Electrocardiogram

TGA:

Transposition of the great arteries

CHD:

Congenital heart disease

ASO:

Arterial switch operation

MDCT:

Multi-detector row computed tomography

VR:

Volume rendering

MPR:

Multiplanar reformation

CTDIvol :

Volume CT dose index

DLP:

Dose-length product

SD:

Standard deviation

TTE:

Transthoracic echocardiography

LCX:

Left circumflex artery

RCA:

Right coronary artery

LAD:

Left anterior descending artery

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Acknowledgements

This work was supported by the Japan Society for the Promotion of Science (JSPS) KAKENHI (17K16452).

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Authors and Affiliations

  1. Department of Radiology, Fukuoka Children’s Hospital, Fukuoka, Japan

    Yuko Odawara, Nobuko Kawamura & Joji Hashimoto

  2. Department of Radiology, Hara Sanshin Hospital, Fukuoka, Japan

    Yuko Odawara

  3. Department of Molecular Imaging and Diagnosis, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

    Yuzo Yamasaki

  4. Department of Cardiology, Fukuoka Children’s Hospital, Fukuoka, Japan

    Shiro Ishikawa

  5. Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan

    Hiroshi Honda

Authors
  1. Yuko Odawara
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  2. Nobuko Kawamura
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  3. Yuzo Yamasaki
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  4. Joji Hashimoto
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  5. Shiro Ishikawa
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  6. Hiroshi Honda
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Corresponding author

Correspondence to Yuko Odawara.

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Conflict of interest

Yamasaki Y: Bayer Healthcare Japan, Modest, Research Grant; Philips Electronics Japan, Modest, Research Grant. Other authors declare that they have no conflict of interest.

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Institutional Review Board approval at Fukuoka Children’s Hospital was obtained.

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Written informed consent was waived due to the retrospective nature of the research.

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Odawara, Y., Kawamura, N., Yamasaki, Y. et al. Evaluation of coronary artery variations using dual-source coronary computed tomography angiography in neonates with transposition of the great arteries. Jpn J Radiol 37, 308–314 (2019). https://doi.org/10.1007/s11604-018-00807-x

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  • DOI: https://doi.org/10.1007/s11604-018-00807-x

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