Disturbances of affective cognition in mood disorders

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  1. Brambilla, P., Perlini, C., Bellani, M., Tomelleri, L., Ferro, A., Cerruti, S., Marinelli, V., Rambaldelli, G., Christodoulou, T., Jogia, J., et al. (2013). Increased salience of gains versus decreased associative learning differentiate bipolar disorder from schizophrenia during incentive decision making. Psychol Med 43, 571–580.

    CAS  Article  Google Scholar 

  2. Broch-Due, I., Kjærstad, H.L., Kessing, L.V., and Miskowiak, K. (2018). Subtle behavioural responses during negative emotion reactivity and down-regulation in bipolar disorder: A facial expression and eye-tracking study. Psychiatry Res 266, 152–159.

    Article  Google Scholar 

  3. Caletti, E., Paoli, R.A., Fiorentini, A., Cigliobianco, M., Zugno, E., Serati, M., Orsenigo, G., Grillo, P., Zago, S., Caldiroli, A., et al. (2013). Neuropsychology, social cognition and global functioning among bipolar, schizophrenic patients and healthy controls: preliminary data. Front Hum Neurosci 7, 661.

    Article  Google Scholar 

  4. Elliott, R., Zahn, R., Deakin, J.F.W., and Anderson, I.M. (2011). Affective cognition and its disruption in mood disorders. Neuropsychopharmacology 36, 153–182.

    Article  Google Scholar 

  5. Frampton, J.E. (2016). Vortioxetine: A review in cognitive dysfunction in depression. Drugs 76, 1675–1682.

    CAS  Article  Google Scholar 

  6. Fried, E.I., and Nesse, R.M. (2014). The impact of individual depressive symptoms on impairment of psychosocial functioning. PLoS ONE 9, e90311.

    Article  Google Scholar 

  7. Gruber, J., Harvey, A.G., and Gross, J.J. (2012). When trying is not enough: Emotion regulation and the effort-success gap in bipolar disorder. Emotion 12, 997–1003.

    Article  Google Scholar 

  8. Gupta, S., Goren, A., Dong, P., and Liu, D. (2016). Prevalence, awareness, and burden of major depressive disorder in urban China. Expert Rev Pharmacoecon Outcomes Res 16, 393–407.

    Article  Google Scholar 

  9. Lembke, A., and Ketter, T.A. (2002). Impaired recognition of facial emotion in mania. Am J Psychiatry 159, 302–304.

    Article  Google Scholar 

  10. Lepping, R.J., Atchley, R.A., Chrysikou, E., Martin, L.E., Clair, A.A., Ingram, R.E., Simmons, W.K., and Savage, C.R. (2016). Neural processing of emotional musical and nonmusical stimuli in depression. PLoS ONE 11, e0156859.

    Article  Google Scholar 

  11. McRae, K., and Gross, J.J. (2020). Emotion regulation. Emotion 20, 1–9.

    Article  Google Scholar 

  12. Miskowiak, K.W., Seeberg, I., Kjaerstad, H.L., Burdick, K.E., Martinez-Aran, A., Del Mar Bonnin, C., Bowie, C.R., Carvalho, A.F., Gallagher, P., Hasler, G., et al. (2019). Affective cognition in bipolar disorder: A systematic review by the ISBD targeting cognition task force. Bipolar Disord 21, 686–719.

    Article  Google Scholar 

  13. Phillips, M.R., Zhang, J., Shi, Q., Song, Z., Ding, Z., Pang, S., Li, X., Zhang, Y., and Wang, Z. (2009). Prevalence, treatment, and associated disability of mental disorders in four provinces in China during 2001–05: an epidemiological survey. Lancet 373, 2041–2053.

    Article  Google Scholar 

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This work was supported by the National Natural Science Foundation of China (81761128032, 81930033, 81771465), the National Key Research and Development Program of China (2016YFC1307100), Clinical Research Plan of Shanghai Hospital Development Center (SHDC12020126), Shanghai Key Project of Science and Technology (2018SHZDZX05), Science and Technology Program of Guangdong (2018B030334001), Sanming Project of Medicine in Shenzhen (SZSM201612006), and the Innovative Research Team of High-level Local Universities in Shanghai.

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Correspondence to Yiru Fang.

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Chen, J., Wang, Z., Li, Z. et al. Disturbances of affective cognition in mood disorders. Sci. China Life Sci. (2021). https://doi.org/10.1007/s11427-020-1898-2

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