Skip to main content
Log in

Profile of Dr. Zhigang Tian

  • Profile
  • From CAS & CAE Members
  • Published:
Science China Life Sciences Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Constantinides, M.G., McDonald, B.D., Verhoef, P.A., and Bendelac, A. (2014). A committed precursor to innate lymphoid cells. Nature 508, 397–401.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Dadi, S., Chhangawala, S., Whitlock, B.M., Franklin, R.A., Luo, C.T., Oh, S.A., Toure, A., Pritykin, Y., Huse, M., Leslie, C.S., et al. (2016). Cancer immunosurveillance by tissue-resident innate lymphoid cells and innate-like T cells. Cell 164, 365–377.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Fan, X., and Rudensky, A.Y. (2016). Hallmarks of tissue-resident lymphocytes. Cell 164, 1198–1211.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Fu, B., Zhou, Y., Ni, X., Tong, X., Xu, X., Dong, Z., Sun, R., Tian, Z., and Wei, H. (2017). Natural killer cells promote fetal development through the secretion of growth-promoting factors. Immunity 47, 1100–1113.e6.

    Article  CAS  PubMed  Google Scholar 

  • Gao, B. (2010). Natural killer group 2 member D, its ligands, and liver disease: good or bad? Hepatology 51, 8–11.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Gao, B., Jeong, W.I., and Tian, Z. (2008). Liver: An organ with predominant innate immunity. Hepatology 47, 729–736.

    Article  CAS  PubMed  Google Scholar 

  • Gasteiger, G., and Rudensky, A.Y. (2014). Interactions between innate and adaptive lymphocytes. Nat Rev Immunol 14, 631–639.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Hou, X., Zhou, R., Wei, H., Sun, R., and Tian, Z. (2009). NKG2D-retinoic acid early inducible-1 recognition between natural killer cells and Kupffer cells in a novel murine natural killer cell-dependent fulminant hepatitis. Hepatology 49, 940–949.

    Article  CAS  PubMed  Google Scholar 

  • Jin, Z., Sun, R., Wei, H., Gao, X., Chen, Y., and Tian, Z. (2011). Accelerated liver fibrosis in hepatitis B virus transgenic mice: involvement of natural killer T cells. Hepatology 53, 219–229.

    Article  CAS  PubMed  Google Scholar 

  • Li, F., Wei, H., Wei, H., Gao, Y., Xu, L., Yin, W., Sun, R., and Tian, Z. (2013). Blocking the natural killer cell inhibitory receptor NKG2A increases activity of human natural killer cells and clears hepatitis B virus infection in mice. Gastroenterology 144, 392–401.

    Article  CAS  PubMed  Google Scholar 

  • McHedlidze, T., Waldner, M., Zopf, S., Walker, J., Rankin, A.L., Schuchmann, M., Voehringer, D., McKenzie, A.N.J., Neurath, M.F., Pflanz, S., et al. (2013). Interleukin-33-dependent innate lymphoid cells mediate hepatic fibrosis. Immunity 39, 357–371.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Peng, H., Jiang, X., Chen, Y., Sojka, D.K., Wei, H., Gao, X., Sun, R., Yokoyama, W.M., and Tian, Z. (2013). Liver-resident NK cells confer adaptive immunity in skin-contact inflammation. J Clin Invest 123, 1444–1456.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Peng, H., and Tian, Z. (2015). Re-examining the origin and function of liver-resident NK cells. Trends Immunol 36, 293–299.

    Article  CAS  PubMed  Google Scholar 

  • Peng, H., and Tian, Z. (2017). Diversity of tissue-resident NK cells. Semin Immunol 31, 3–10.

    Article  CAS  PubMed  Google Scholar 

  • Sun, C., Fu, B., Gao, Y., Liao, X., Sun, R., Tian, Z., and Wei, H. (2012). TGF-beta1 down-regulation of NKG2D/DAP10 and 2B4/SAP expression on human NK cells contributes to HBV persistence. PLoS Pathog 8, e1002594.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Tang, L., Peng, H., Zhou, J., Chen, Y., Wei, H., Sun, R., Yokoyama, W.M., and Tian, Z. (2016). Differential phenotypic and functional properties of liver-resident NK cells and mucosal ILC1s. J Autoimmunity 67, 29–35.

    Article  CAS  Google Scholar 

  • Wang, X., Sun, R., Wei, H., and Tian, Z. (2013). High-mobility group box 1 (HMGB1)-toll-like receptor (TLR)4-interleukin (IL)-23-IL-17A axis in drug-induced damage-associated lethal hepatitis: Interaction of γδ T cells with macrophages. Hepatology 57, 373–384.

    Article  CAS  PubMed  Google Scholar 

  • Wu, P., Wu, D., Ni, C., Ye, J., Chen, W., Hu, G., Wang, Z., Wang, C., Zhang, Z., Xia, W., et al. (2014). γδT17 cells promote the accumulation and expansion of myeloid-derived suppressor cells in human colorectal cancer. Immunity 40, 785–800.

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Zhang, Q., Bi, J., Zheng, X., Chen, Y., Wang, H., Wu, W., Wang, Z., Wu, Q., Peng, H., Wei, H., et al. (2018). Blockade of the checkpoint receptor TIGIT prevents NK cell exhaustion and elicits potent anti-tumor immunity. Nat Immunol 19, 723–732.

    Article  CAS  PubMed  Google Scholar 

Download references

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Profile of Dr. Zhigang Tian. Sci. China Life Sci. 61, 1474–1476 (2018). https://doi.org/10.1007/s11427-018-9366-3

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11427-018-9366-3

Navigation