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Science China Life Sciences

, Volume 61, Issue 3, pp 355–357 | Cite as

Celastrol specifically inhibits the activation of NLRP3 inflammasome

  • Xuesong Sang
  • Yihui Chen
  • Wei Chen
  • Jing Xie
  • Guangxun Meng
  • Jin Zhong
  • Taisheng Li
  • Ailing Lu
Letter to the Editor

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Notes

Acknowledgements

This work was supported by the Natural Science Foundation of China (31570895, 31370892, 91429307), National Key Basic Research Programs (2015CB554302, 2014CB541905), and International Partnership Program of Chinese Academy of Sciences (153831KYSB20160009).

Supplementary material

11427_2017_9048_MOESM1_ESM.docx (33 kb)
MATERIALS AND METHODS

References

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Copyright information

© Science China Press and Springer-Verlag GmbH Germany, part of Springer Nature 2017

Authors and Affiliations

  • Xuesong Sang
    • 1
    • 2
  • Yihui Chen
    • 1
  • Wei Chen
    • 1
  • Jing Xie
    • 3
    • 4
  • Guangxun Meng
    • 1
  • Jin Zhong
    • 1
  • Taisheng Li
    • 3
    • 4
  • Ailing Lu
    • 1
  1. 1.CAS Key Laboratory of Molecular Virology & Immunology, Institute Pasteur of ShanghaiChinese Academy of SciencesShanghaiChina
  2. 2.School of Life SciencesShanghai UniversityShanghaiChina
  3. 3.Department of Infectious Diseases, Peking Union Medical College HospitalPeking Union Medical College and Chinese Academy of Medical SciencesBeijingChina
  4. 4.Clinical Immunology CenterChinese Academy of Medical SciencesBeijingChina

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