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Journal of Natural Medicines

, Volume 71, Issue 1, pp 299–304 | Cite as

Pteleifolols A–E, acetophenone di-C-glycosides and a benzopyran dimer from the leaves of Melicope pteleifolia

  • Ken-ichi Nakashima
  • Naohito Abe
  • Fang-Rong Chang
  • Makoto Inoue
  • Masayoshi Oyama
Note
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Accepted:
  • 228 Downloads

Abstract

Four new acetophenone di-C-glycosides, pteleifolols A–D (1–4) and a new dimeric benzopyran, pteleifolol E (5), were isolated from the leaves of Melicope pteleifolia. Seven known compounds, including 2,4,6-trihydroxyacetophenone-3,5-di-C-glucopyranoside (6), were also isolated. Structures of the new compounds (1–5) were established by using spectroscopic and spectrometric techniques, including 1D and 2D nuclear magnetic resonance (NMR), UV, and high-resolution electrospray ionization mass spectrometry (HR-ESI–MS) data. Pteleifolols A–D (1–4) were E-p-coumaroyl, Z-p-coumaroyl, E-feruloyl, and benzoyl esters of 6, respectively. Pteleifolol E (5) was a dichromene dimerized through a C2 unit.

Keywords

Melicope pteleifolia Rutaceae Acetophenone Dimeric benzopyran Pteleifolols A–E 
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Copyright information

© The Japanese Society of Pharmacognosy and Springer Japan 2016

Authors and Affiliations

  1. 1.Laboratory of Medicinal Resources, School of PharmacyAichi Gakuin UniversityNagoyaJapan
  2. 2.Department of Bioactive Molecules, Laboratory of PharmacognosyGifu Pharmaceutical UniversityGifuJapan
  3. 3.Graduate Institute of Natural Products, College of PharmacyKaohsiung Medical UniversityKaohsiungTaiwan

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