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Der Gastroenterologe

, Volume 12, Issue 2, pp 150–151 | Cite as

PPI reduzieren Blutungsrisiko unter Phenprocoumon

  • Mark Ellrichmann
Journal Club
  • 111 Downloads

Concomitant PPI administration reduces risk of upper gastrointestinal bleeding in patients on Warfarin

Notes

Interessenkonflikt

M. Ellrichmann gibt an, dass kein Interessenkonflikt besteht.

Literatur

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    Lin KJ, Hernández-Díaz S, García Rodríguez LA (2011) Acid suppressants reduce risk of gastrointestinal bleeding in patients on antithrombotic or anti-inflammatory therapy. Gastroenterology 141(1):71–79. doi: 10.1053/j.gastro.2011.03.049 CrossRefPubMedGoogle Scholar
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    Chan EW, Lau WC, Leung WK, Mok MT, He Y, Tong TS, Wong IC (2015) Prevention of dabigatran-related gastrointestinal bleeding with gastroprotective agents: A population-based study. Gastroenterology 149(3):586–595.e3. doi: 10.1053/j.gastro.2015.05.002 CrossRefPubMedGoogle Scholar
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    Li XQ, Andersson TB, Ahlström M, Weidolf L (2004) Comparison of inhibitory effects of the proton pump-inhibiting drugs omeprazole, esomeprazole, lansoprazole, pantoprazole, and rabeprazole on human cytochrome P450 activities. Drug Metab Dispos 32(8):821–827CrossRefPubMedGoogle Scholar
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    Henriksen DP, Stage TB, Hansen MR, Rasmussen L, Damkier P, Pottegård A (2015) The potential drug-drug interaction between proton pump inhibitors and warfarin. Pharmacoepidemiol Drug Saf 24(12):1337–1340. doi: 10.1002/pds.3881 CrossRefPubMedGoogle Scholar

Copyright information

© Springer Medizin Verlag GmbH 2017

Authors and Affiliations

  1. 1.Interdisziplinäre Endoskopie Klinik für Innere Medizin 1Universitätsklinikum Schleswig-Holstein, Campus KielKielDeutschland

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