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Larvicidal effect from different Annonaceae species on Culex quinquefasciatus

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Abstract

The recent outbreaks of mosquito-borne diseases highlighted the pivotal importance of mosquito vector control in tropical areas worldwide. Several strategies have been developed to control vector populations and disease transmission in endemic areas. The steps to obtain natural active compounds involve the pre-selection in a biological model and subsequently evaluation on specific models. The present study reports the evaluation of 35 extracts, fractions, and essential oils obtained from five species from the Annonaceae family on Artemia salina and Culex quinquefasciatus. The A. salina results were used as a pre-screening for larvicidal test about mosquitoes. A correlation of biological activity in both bioassays was observed for the hydroethanolic extracts and their respective hexane and chloroform fractions of the leaves of Annona species, except A. nutans. The same correlation was also observed for all tested essential oils and petroleum ether extracts from Duguetia species. It was possible to limit an interval of lethality about A. salina, which has a corresponding range to the larvicidal test against the mosquito. The main components present in D. lanceolata essential oil or enriched fraction were α-selinene, aristolochene, (E)-caryophyllene, and (E)-calamenene. For D. furfuracea, the main components present of the underground parts were (E)-asarone, 2,4,5-trimethoxystyrene, spathulenol, and bicyclogermacrene for aerial parts. The A. salina test could be used as a model for the pre-screening of larvicidal activity.

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Authors and Affiliations

  1. Campus Centro-Oeste Dona Lindu, Universidade Federal de São João del Rei, Av. Sebastião Gonçalves Coelho, 400, Divinópolis, MG, 35501-296, Brazil

    Débora Soares Maia, Camila Ferreira Lopes, Aline Aparecida Saldanha, Nathália Lucca Silva, Stênio Nunes Alves & João Máximo de Siqueira

  2. Laboratório de Produtos Naturais e Espectrometria de Massas, Faculdade de Ciências Farmacêuticas, Alimentação e Nutrição, Universidade Federal de Mato Grosso do Sul, Campo Grande, MS, 79070-900, Brazil

    Ângela Lúcia Bagnatori Sartori, Carlos Alexandre Carollo & Denise Brentan Silva

  3. Departamento de Ciências Naturais, Universidade Federal São João Del Rei, São João Del Rei, MG, 36301-160, Brazil

    Marcos Guerra Sobral

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  1. Débora Soares Maia
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  2. Camila Ferreira Lopes
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  3. Aline Aparecida Saldanha
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  4. Nathália Lucca Silva
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  7. Marcos Guerra Sobral
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  8. Stênio Nunes Alves
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Correspondence to Débora Soares Maia.

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Maia, D.S., Lopes, C.F., Saldanha, A.A. et al. Larvicidal effect from different Annonaceae species on Culex quinquefasciatus. Environ Sci Pollut Res 27, 36983–36993 (2020). https://doi.org/10.1007/s11356-020-08997-6

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