Skip to main content

Advertisement

SpringerLink
Log in

Comparison of Vela and holmium laser enucleation of the prostate: a retrospective clinical trial with a 12-month follow-up

  • Urology - Original Paper
  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

Abstract

Purpose

This study aimed to estimate the validity and applicability of Vela laser enucleation of the prostate (VoLEP) in the management of benign prostatic hyperplasia (BPH).

Methods

A retrospective chart review of 112 patients with BPH who underwent VoLEP (n = 60) or holmium laser enucleation of the prostate (HoLEP) (n = 56) was conducted at our institution from January 2015 to June 2015. The general and perioperative characteristics of the patients were collected. The 12-month follow-up data, including the lower urinary tract symptom (LUTS) indexes (International Prostate Symptom Score [I-PSS], quality-of-life [QoL] score and maximum flow rate [Qmax]), as well as rates of perioperative and late complications, were analyzed.

Results

No significant differences were observed in pre- and perioperative parameters, including operation time (58.05 ± 10.14 vs. 60.14 ± 12.30 min, P = 0.44), serum sodium decrease (3.49 ± 0.83 vs. 3.48 ± 0.84 mmol/L, P = 0.97), hemoglobin decrease (1.28 ± 0.38 vs. 1.24 ± 0.77 g/dL, P = 0.71), catheterization time (3.63 ± 1.10 vs. 3.89 ± 1.11 days, P = 0.21) and hospital stay (4.57 ± 1.25 vs. 4.68 ± 1.18 days, P = 0.63) between the two groups of patients. Compared with the HoLEP group, the noise during operation was lower in VoLEP group (47.22 ± 10.31 vs. 59.45 ± 9.65 db, P < 0.05). During 1, 6 and 12 months of follow-up visits, the LUTS indexes (I-PSS, QoL score and Qmax) were remarkably improved in both groups when comparing with the baseline values. Furthermore, LUTS indexes were comparable in both groups (P > 0.05).

Conclusion

Similarly as the holmium laser, the Vela laser is a potent, safe, efficient durable and surgical treatment option for minimally invasive surgery in patients with BPH-induced LUTS.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1

Similar content being viewed by others

References

  1. Madersbacher S, Marberger M (1999) Is transurethral resection of the prostate still justified? BJU Int 83(3):227–237

    Article  CAS  PubMed  Google Scholar 

  2. Ahyai SA, Gilling P, Kaplan SA, Kuntz RM, Madersbacher S, Montorsi F, Speakman MJ, Stief CG (2010) Meta-analysis of functional outcomes and complications following transurethral procedures for lower urinary tract symptoms resulting from benign prostatic enlargement. Eur Urol 58(3):384–397. https://doi.org/10.1016/j.eururo.2010.06.005

    Article  PubMed  Google Scholar 

  3. Elzayat EA, Habib EI, Elhilali MM (2005) Holmium laser enucleation of the prostate: a size-independent new “gold standard”. Urology 66(5 Suppl):108–113. https://doi.org/10.1016/j.urology.2005.06.006

    Article  PubMed  Google Scholar 

  4. Sun N, Fu Y, Tian T, Gao J, Wang Y, Wang S, An W (2014) Holmium laser enucleation of the prostate versus transurethral resection of the prostate: a randomized clinical trial. Int Urol Nephrol 46(7):1277–1282

    Article  PubMed  Google Scholar 

  5. Elshal AM, El-Assmy A, Mekkawy R, Taha D-E, El-Nahas AR, Laymon M, El-Kappany H, Ibrahiem E-H (2017) Prospective controlled assessment of men’s sexual function changes following Holmium laser enucleation of the prostate for treatment of benign prostate hyperplasia. Int Urol Nephrol 49(10):1741–1749

    Article  PubMed  Google Scholar 

  6. Kwon T, Park S, Park S, Moon KH (2017) Metabolic syndrome is predictive of lower urinary tract symptom improvement after holmium laser enucleation of the prostate for benign prostatic obstruction. Int Urol Nephrol 49(7):1105–1110

    Article  PubMed  Google Scholar 

  7. Tan AH, Gilling PJ (2003) Holmium laser prostatectomy. BJU Int 92(6):527–530

    Article  CAS  PubMed  Google Scholar 

  8. Chen YB, Chen Q, Wang Z, Peng YB, Ma LM, Zheng DC, Cai ZK, Li WJ, Ma LH (2013) A prospective, randomized clinical trial comparing plasmakinetic resection of the prostate with holmium laser enucleation of the prostate based on a 2-year followup. J Urol 189(1):217–222. https://doi.org/10.1016/j.juro.2012.08.087

    Article  PubMed  Google Scholar 

  9. Michalak J, Tzou D, Funk J (2015) HoLEP: the gold standard for the surgical management of BPH in the 21(st) Century. Am J Clin Exp Urol 3(1):36–42

    PubMed  PubMed Central  Google Scholar 

  10. Chen Q, Chen YB, Wang Z, Peng YB, Zheng DC, Cai ZK, Li WJ, Zhou J (2012) An improved morcellation procedure for holmium laser enucleation of the prostate. J Endourol 26(12):1625–1628. https://doi.org/10.1089/end.2012.0265

    Article  PubMed  PubMed Central  Google Scholar 

  11. Oelke M, Bachmann A, Descazeaud A, Emberton M, Gravas S, Michel MC, N’Dow J, Nordling J, de la Rosette JJ, European Association of U (2013) EAU guidelines on the treatment and follow-up of non-neurogenic male lower urinary tract symptoms including benign prostatic obstruction. Eur Urol 64(1):118–140. https://doi.org/10.1016/j.eururo.2013.03.004

    Article  PubMed  Google Scholar 

  12. Berry SJ, Coffey DS, Walsh PC, Ewing LL (1984) The development of human benign prostatic hyperplasia with age. J Urol 132(3):474–479

    Article  CAS  PubMed  Google Scholar 

  13. Geavlete B, Stanescu F, Iacoboaie C, Geavlete P (2013) Bipolar plasma enucleation of the prostate vs open prostatectomy in large benign prostatic hyperplasia cases—a medium term, prospective, randomized comparison. BJU Int 111(5):793–803. https://doi.org/10.1111/j.1464-410X.2012.11730.x

    Article  CAS  PubMed  Google Scholar 

  14. Gratzke C, Schlenker B, Seitz M, Karl A, Hermanek P, Lack N, Stief CG, Reich O (2007) Complications and early postoperative outcome after open prostatectomy in patients with benign prostatic enlargement: results of a prospective multicenter study. J Urol 177(4):1419–1422. https://doi.org/10.1016/j.juro.2006.11.062

    Article  PubMed  Google Scholar 

  15. Kuntz RM, Lehrich K, Ahyai SA (2008) Holmium laser enucleation of the prostate versus open prostatectomy for prostates greater than 100 grams: 5-year follow-up results of a randomised clinical trial. Eur Urol 53(1):160–166. https://doi.org/10.1016/j.eururo.2007.08.036

    Article  PubMed  Google Scholar 

  16. Lee NG, Xue H, Lerner LB (2012) Trends and attitudes in surgical management of benign prostatic hyperplasia. Can J Urol 19(2):6170–6175

    PubMed  Google Scholar 

  17. Naspro R, Suardi N, Salonia A, Scattoni V, Guazzoni G, Colombo R, Cestari A, Briganti A, Mazzoccoli B, Rigatti P, Montorsi F (2006) Holmium laser enucleation of the prostate versus open prostatectomy for prostates > 70 g: 24-month follow-up. Eur Urol 50(3):563–568. https://doi.org/10.1016/j.eururo.2006.04.003

    Article  PubMed  Google Scholar 

  18. Kuntz RM, Lehrich K (2002) Transurethral holmium laser enucleation versus transvesical open enucleation for prostate adenoma greater than 100 gm: a randomized prospective trial of 120 patients. J Urol 168(4):1465–1469. https://doi.org/10.1097/01.ju.0000027901.47718.fc

    Article  PubMed  Google Scholar 

  19. Ginsberg SH, Pantin E, Kraidin J, Solina A, Panjwani S, Yang G (2013) Noise levels in modern operating rooms during surgery. J Cardiothorac Vasc Anesth 27(3):528–530. https://doi.org/10.1053/j.jvca.2012.09.001

    Article  PubMed  Google Scholar 

  20. Shapiro RA, Berland T (1972) Noise in the operating room. N Engl J Med 287(24):1236–1238. https://doi.org/10.1056/NEJM197212142872407

    Article  CAS  PubMed  Google Scholar 

  21. Engelmann CR, Neis JP, Kirschbaum C, Grote G, Ure BM (2014) A noise-reduction program in a pediatric operation theatre is associated with surgeon’s benefits and a reduced rate of complications: a prospective controlled clinical trial. Ann Surg 259(5):1025–1033. https://doi.org/10.1097/SLA.0000000000000253

    Article  PubMed  Google Scholar 

Download references

Acknowledgements

This study was funded by grants from the Key Disciplines Group Construction Project of the Pudong Health Bureau of Shanghai (Grant No. PWZxq2014-11) and project of Shanghai Committee of Science and Technology (Grant No. 15DZ1941503).

Author information

Author notes

  1. Meng Gu and Chong Liu have contributed equally to this work.

Authors and Affiliations

  1. Department of Urology, Shanghai Ninth People’s Hospital, Shanghai Jiao Tong University School of Medicine, 639 Zhizaoju Road, Shanghai, 200011, People’s Republic of China

    Meng Gu, Chong Liu, Yan-bo Chen, Huan Xu, Shi Fu, Qi Chen & Zhong Wang

Authors
  1. Meng Gu
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Chong Liu
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Yan-bo Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Huan Xu
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Shi Fu
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Qi Chen
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Zhong Wang
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding authors

Correspondence to Qi Chen or Zhong Wang.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Gu, M., Liu, C., Chen, Yb. et al. Comparison of Vela and holmium laser enucleation of the prostate: a retrospective clinical trial with a 12-month follow-up. Int Urol Nephrol 50, 819–823 (2018). https://doi.org/10.1007/s11255-018-1840-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11255-018-1840-y

Keywords

Search

Navigation