International Urology and Nephrology

, Volume 50, Issue 4, pp 625–632 | Cite as

Factors predicting success after microsurgical vasovasostomy

  • Marco Cosentino
  • Maria F. Peraza
  • Alvaro Vives
  • Josvany Sanchez
  • Daniel Moreno
  • Judith Perona
  • Gerardo Ortiz
  • Maria Alcoba
  • Eduardo Ruiz
  • Joaquim Sarquella
Urology - Original Paper



To identify factors predicting success and analyze critically the status of microsurgical double-layer vasovasostomy using predictive models.


A cohort of 263 patients treated at our institution for vasectomy reversal between 1986 and 2010 was included in our study, and the literature was reviewed. Inclusion criteria were previous bilateral vasectomy and presence of at least two postoperative semen analyses; patients reporting pregnancy without a postoperative semen analysis were excluded. A double-layer, microscope-assisted, tension-free anastomosis vasovasostomy was performed approximating mucosa to mucosa and muscle to muscle with a 10-0 non-absorbable suture. A multivariate logistic regression backward stepwise model was used to predict combined success, and a predictive model was calculated with remaining variables.


Mean age was of 41.6 years (SD 7.1); mean duration of obstruction 7.2 years (SD 6.7). On multivariate analysis, uni- or bilateral granuloma and Silber grade of I–III were variable identified predicting higher probability to success (OR 3.105; 95% CI 1.108–8.702; p = 0.031 and OR 4.795; 95% CI 2.117–10.860; p < 0.001, respectively).


Based on our results, some factors predicting success after vasovasostomy surgery are known but others remain unknown; our predictive model may easily predict patency and success after this surgery and offers a concrete assistance in counseling patients.


Vasectomy reversal Patency Microsurgery Predictive factors 



Vasovasostomy study group







To Cristina Esquinas Lopez for statistical analysis and for her patience.

Compliance with ethical standards

Conflict of interest

All authors declare that there is no conflict of interest.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.


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Copyright information

© Springer Science+Business Media B.V., part of Springer Nature 2018

Authors and Affiliations

  • Marco Cosentino
    • 1
  • Maria F. Peraza
    • 1
  • Alvaro Vives
    • 1
  • Josvany Sanchez
    • 1
  • Daniel Moreno
    • 1
  • Judith Perona
    • 2
  • Gerardo Ortiz
    • 3
  • Maria Alcoba
    • 4
  • Eduardo Ruiz
    • 1
  • Joaquim Sarquella
    • 1
  1. 1.Andrology Department, Fundacio PuigvertUniversitat Autonoma de BarcelonaBarcelonaSpain
  2. 2.Anaesthesia Department, Hospital de Sant PauUniversitat Autonoma de BarcelonaBarcelonaSpain
  3. 3.The American British Cowday Medical CenterCiudad MéxicoMexico
  4. 4.Urology DepartmentHospital Universitario Fundación Jiménez DíazMadridSpain

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