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A collecting duct carcinoma producing carcinoembryonic antigen and Ca-125 in a 29-year-old woman

  • Urology - Case Report
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Abstract

Collecting duct carcinoma is a rare renal malignant neoplasm, arising from the medullary collecting duct and accounting for less than 1 % of renal cell carcinomas. It is more common in middle-aged men and is usually presented with hematuria, abdominal mass and back or flank pain. Its immunohistochemical analysis detects the expression of various markers, such as low and high molecular weight keratins, Ulex europaeus agglutinin-1, epithelial membrane antigen and peanut lectin. Here, we present a case of a 29-year-old woman with CDC presented with back pain and supraclavicular lymphadenopathy that produced carcinoembryonic antigen and CA-125.

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References

  1. Matz LR, Latham BI, Fabian VA, Vivian JB (1997) Collecting duct carcinoma of the kidney: a report of three cases and review of the literature. Pathology 29:354–359

    Article  CAS  PubMed  Google Scholar 

  2. Milowsky MI, Rosmarin A, Tickoo SK, Papanicolaou N, Nanus DM (2002) Active chemotherapy for collecting duct carcinoma of the kidney: a case report and review of the literature. Cancer 94:111–116

    Article  PubMed  Google Scholar 

  3. Kuroda N, Toi M, Hiroi M, Enzan H (2002) Review of collecting duct carcinoma with focus on clinical and pathobiological aspects. Histol Histopathol 17:1329–1334

    CAS  PubMed  Google Scholar 

  4. Orsola A, Trias I, Raventós CX, Español I, Cecchini L, Orsola I (2005) Renal collecting (bellini) duct carcinoma dispalys similar characteristics to upper tract urothelial cell carcinoma. Urology 65:49–54

    Article  CAS  PubMed  Google Scholar 

  5. Srigley JR, Delahunt B (2009) Uncommon and recently described renal carcinomas. Mod Pathol 22:S2–S23

    Article  PubMed  Google Scholar 

  6. Truong LD, Shen SS (2011) Immunohistochemical diagnosis of renal neoplasms. Arch Pathol Lab Med 135:92–109

    PubMed  Google Scholar 

  7. Yoon SK, Nam KJ, Rha SH, Kim JK, Cho KS, Kim B, Kim KH, Kim KA (2006) Collecting duct carcinoma of the kidney: CT and pathologic correlation. Eur J Radiol 57:453–460

    Article  PubMed  Google Scholar 

  8. Gupta R, Billis A, Shah RB, Moch H, Osunkoya AO, Jochum W, Hes O, Bacchi CE, de Castro MG, Hansel DE, Zhou M, Vankalakunti M, Salles PG, Cabrera RA, Gown AM, Amin MB (2012) Carcinoma of the collecting ducts of Bellini and renal medullary carcinoma: clinicopathologic analysis of 52 cases of rare aggressive subtypes of renal cell carcinoma with a focus on their interrelationship. Am J Surg Pathol 36:1265–1278

    Article  PubMed  Google Scholar 

  9. Kobayashi N, Matsuzaki O, Shirai S, Aoki I, Yao M, Nagashima Y (2008) Collecting duct carcinoma of the kidney: an immunohistochemical evaluation of the use of antibodies for differential diagnosis. Hum Pathol 39:1350–1359

    Article  CAS  PubMed  Google Scholar 

  10. Hammarström S (1999) The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. Semin Cancer Biol 9:67–81

    Article  PubMed  Google Scholar 

  11. Nap M (1998) Immunohistochemistry of CA 125. Unusual expression in normal tissues, distribution in the human fetus and questions around its application in diagnostic pathology. Int J Biol Markers 13:210–215

    CAS  PubMed  Google Scholar 

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Conflict of interest

The authors declare that they have no conflict of interest.

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Authors and Affiliations

  1. Second Department of Medical Oncology, “Agios Savvas” Anticancer Hospital, 171 Alexandras Avenue, 11522, Athens, Greece

    Nikolaos Tsoukalas, Maria Tolia, Dimitrios Tryfonopoulos, Georgios Lypas, Christos Panopoulos, Vasileios Barbounis, Georgios Koumakis & Anna Efremidis

  2. Department of Medical Oncology, “401” General Military Hospital, 138 Mesogeion Avenue and Katehaki Avenue, 11525, Athens, Greece

    Nikolaos Tsoukalas

  3. Second Department of Propaedeutic Surgery, “Laiko” General Hospital, Medical School, National and Kapodistrian University of Athens, 17 Agiou Thoma Street, 11527, Athens, Greece

    Ioannis D. Kostakis

  4. 27 Achridos Street, Kato Patissia, 11144, Athens, Greece

    Ioannis D. Kostakis

Authors
  1. Nikolaos Tsoukalas
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  2. Ioannis D. Kostakis
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  3. Maria Tolia
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  4. Dimitrios Tryfonopoulos
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  5. Georgios Lypas
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  6. Christos Panopoulos
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  7. Vasileios Barbounis
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  8. Georgios Koumakis
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  9. Anna Efremidis
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Corresponding author

Correspondence to Ioannis D. Kostakis.

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Tsoukalas, N., Kostakis, I.D., Tolia, M. et al. A collecting duct carcinoma producing carcinoembryonic antigen and Ca-125 in a 29-year-old woman. Int Urol Nephrol 46, 1313–1316 (2014). https://doi.org/10.1007/s11255-014-0660-y

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  • DOI: https://doi.org/10.1007/s11255-014-0660-y

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