Abstract
West Nile virus (WNV) is a mosquito-borne disease, usually present as a symptomatic disease but can cause various clinical signs ranged from mild fever to severe encephalitis and death in various animals and humans. In Egypt, the epidemiological data about WNV infection in different animal species particularly in domestic ruminants are scarce. The present study aimed to investigate the seroprevalence of WNV in cattle, buffalo, camel, sheep, and goats at some Governorates northern Egypt. In total, 360 serum samples (100 cattle, 50 buffalo, 50 camels, 85 sheep, and 75 goats) were examined using ELISA. The results revealed that the seroprevalence of WNV among ruminants was highly significant (P = 0.03) at Kafr El Sheikh Governorate (17.6%) in comparison with other the Governorates. Besides, the seroprevalence of WNV antibodies significantly differed between the examined species (P = 0.0001); it was 22%, 0%, 40%, 3.5%, and 5.3% in cattle, buffalo, camel, sheep, and goats, respectively. This is the first study to confirm that domestic ruminants act as a reservoir in the epidemiology of WNV infection and represent a risk for human and equine infections in Egypt.
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References
Albayrak, H., and Ozan, E., 2013. Seroepidemiological study of west nile virus and rift valley Fever virus in some of Mammalian species (herbivores) in northern Turkey, Journal of arthropod-borne diseases, 7, 90-93
Baba, S.S., NNnadi, O.D., Hamman, K.D., Saidu, A., El Yuguda, A., and Oderinde, B.S., 2014. Preliminary study on the prevalence of West Nile virus antibody among horses, donkeys and camels in Borno State, Nigeria, Journal of Applied Virology, 3, 39-45
Beck, C., Jimenez-Clavero, M.A., Leblond, A., Durand, B., Nowotny, N., Leparc-Goffart, I., Zientara, S., Jourdain, E., and Lecollinet, S., 2013. Flaviviruses in Europe: complex circulation patterns and their consequences for the diagnosis and control of West Nile disease, International Journal of Environmental Research and Public Health, 10, 6049-6083
Beck, C., Lowenski, S., Durand, B., Bahuon, C., Zientara, S., and Lecollinet, S., 2017. Improved reliability of serological tools for the diagnosis of West Nile fever in horses within Europe, PLoS neglected tropical diseases, 11, e0005936
Cardinale, E., Bernard, C., Lecollinet, S., Rakotoharinome, V.M., Ravaomanana, J., Roger, M., Olive, M.-M., Meenowa, D., Jaumally, M.R., and Melanie, J., 2017. West Nile virus infection in horses, Indian ocean, Comparative immunology, microbiology and infectious diseases, 53, 45-49
Corwin, A., Habib, M., Olson, J., Scott, D., Ksiazek, T., and Watts, D.M., 1992. The prevalence of arboviral, rickettsial, and Hantaan-like viral antibody among schoolchildren in the Nile river delta of Egypt, Transactions of the Royal Society of Tropical medicine and Hygiene, 86, 677-679
Darwish, M.A., Hoogstraal, H., Roberts, T.J., Ahmed, I.P., and Omar, F., 1983. A sero-epidemiological survey for certain arboviruses (Togaviridae) in Pakistan, Transactions of the Royal Society of Tropical medicine and Hygiene, 77, 442-445
Davoust, B., Maquart, M., Roqueplo, C., Gravier, P., Sambou, M., Mediannikov, O., and Leparc-Goffart, I., 2016. Serological survey of West Nile virus in domestic animals from Northwest Senegal, Vector-Borne and Zoonotic Diseases, 16, 359-361
Deegan, C.S., Burns, J.E., Huguenin, M., Steinhaus, E.Y., Panella, N.A., Beckett, S., and Komar, N., 2005. Sentinel pigeon surveillance for West Nile virus by using lard-can traps at differing elevations and canopy cover classes, Journal of medical entomology, 42, 1039-1044
Erol, N., Gürçay, M., Kırdar, S., Ertuğrul, B., Gür, S., Koç, B., and Tan, M., 2016. A Serological Investigation of West Nile Virus Infections in Various Animal Species and Humans in Western Turkey, Israel Journal of Veterinary Medicine, 71, 42-46
Giadinis, N.D., Katsoulos, P.D., Chochlakis, D., Tselentis, Y., Ntais, P., Lafi, S.Q., Karatzias, H., and Psaroulaki, A., 2015. Serological investigation for West Nile virus, Anaplasma ovisand Leishmania infantum in Greek cattle, Veterinaria italiana, 51, 205-209
Hassine, T.B., Amdouni, J., Monaco, F., Savini, G., Sghaier, S., Selimen, I.B., Chandoul, W., Hamida, K.B., and Hammami, S., 2017. Emerging vector-borne diseases in dromedaries in Tunisia: West Nile, bluetongue, epizootic haemorrhagic disease and Rift Valley fever, Onderstepoort Journal of Veterinary Research, 84, 1-3
Jupp, P.G., 2001. The ecology of West Nile virus in South Africa and the occurrence of outbreaks in humans, Annals of the New York Academy of Sciences, 951, 143-152
Mariéa, J., Lafranceb, B., Maquartc, M., Mulotd, B., Leclercd, A., Davouste, B., and Leparc-Goffartf, I., 2016. West Nile virus circulation in Djibouti, Abstracts/International Journal of Infectious Diseases 53S, 4, 163
Olaleye, O., Omilabu, S., Ilomechina, E., and Fagbami, A., 1990. A survey for haemagglutination-inhibiting antibody to West Nile virus in human and animal sera in Nigeria, Comparative immunology, microbiology and infectious diseases, 13, 35-39
Oluwayelu, D., Adebiyi, A., and Tomori, O., 2018. Endemic and emerging arboviral diseases of livestock in Nigeria: a review, Parasites & vectors, 11, 337
Ozdenerol, E., Taff, G.N., and Akkus, C., 2013. Exploring the spatio-temporal dynamics of reservoir hosts, vectors, and human hosts of West Nile virus: a review of the recent literature, International Journal of Environmental Research and Public Health, 10, 5399-5432
Sayed-Ahmed, M., 2016. Incidence History of West Nile Virus in Africa and Middle East, With an Emphasis on Egypt: A Review, J Dairy Vet Anim Res, 3, 00080
Selim, A., Radwan, A., Arnaout, F., Hanem Khater, F.A., 2020a. The Recent Update of the Situation of West Nile Fever among Equids in Egypt after Three Decades of Missing Information, Pakistan Veterinary Journal, DOI: https://doi.org/10.29261/pakvetj/2020.20-008
Selim, A., Radwan, A., and Hamouda, F., 2020b. Seroprevalence and Molecular Characterization of West Nile Virus in Egypt, Comparative immunology, microbiology and infectious diseases, 71:101473
Sotelo, E., Llorente, F., Rebollo, B., Camuñas, A., Venteo, A., Gallardo, C., Lubisi, A., Rodríguez, M.J., Sanz, A.J., and Figuerola, J., 2011. Development and evaluation of a new epitope-blocking ELISA for universal detection of antibodies to West Nile virus, Journal of virological methods, 174, 35-41
Sule, W.F., Oluwayelu, D.O., Hernández-Triana, L.M., Fooks, A.R., Venter, M., and Johnson, N., 2018. Epidemiology and ecology of West Nile virus in sub-Saharan Africa, Parasites & vectors, 11, 414
Ulloa, A., Ferguson, H.H., Méndez-Sánchez, J.D., Danis-Lozano, R., Casas-Martínez, M., Bond, J.G., García-Zebadúa, J.C., Orozco-Bonilla, A., Juárez-Ordaz, J.A., and Farfan-Ale, J.A., 2009. West Nile virus activity in mosquitoes and domestic animals in Chiapas, México, Vector-Borne and Zoonotic Diseases, 9, 555-560
Zayed, A.B., Britch, S.C., Soliman, M.I., and Linthicum, K.J., 2015. Mosquitoes and the environment in Nile delta villages with previous Rift Valley fever activity, Journal of the American Mosquito Control Association, 31, 139-149
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The authors wish to thank the Science and Technology Development Fund (STDF) for their financial support through the project Number (34763) to complete this work.
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Selim, A., Abdelhady, A. The first detection of anti-West Nile virus antibody in domestic ruminants in Egypt. Trop Anim Health Prod 52, 3147–3151 (2020). https://doi.org/10.1007/s11250-020-02339-x
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DOI: https://doi.org/10.1007/s11250-020-02339-x