Skip to main content

Advertisement

Log in

The characteristics of coronary stenosis in 11,267 patients from Southwest China: a retrospective study

  • Published:
Journal of Thrombosis and Thrombolysis Aims and scope Submit manuscript

Abstract

The characteristics of coronary stenosis vary among the different countries or areas. 11,267 patients who have undergone coronary angiography (CAG) from three Southwest China hospitals were investigated. Patient characteristics, coronary stenosis and stent-implant information were recorded and analyzed according to two criteria: “visible stenosis” and “≥ 50% stenosis”. The patients who have undergone CAG increased year by year, with patients from 60 to 69 years-old taking the highest ratio (34.69%). Based on the “≥ 50% stenosis” criteria, the stenotic frequency was 40.54% for Southwest China patients getting CAG. Only 8.14% patients suffered ≥ 3 stenotic vessels, while 11.58 and 20.82% patients had 2 or 1 stenotic vessel, respectively. However, when using the “visible stenosis” criteria, the stenotic frequency increased to 64.68%. The prevalence of stenosis increased with age based on the “visible stenosis” criteria. There were more male patients with stenosis than female except patients over 80 years old. The stenosis affected almost all main coronary arteries and their branches, with the most affected artery being the left anterior descending artery. There were 3246 cases (28.8%) implanted with 5423 stents with a concurrent age-dependent increasing tendency for stent-implant frequency and average implanted stent number. The numbers of patients who have undergone CAG and suffered from CVD increased rapidly. In these patients, positive rate of CAG was 64.67%, which increased to 72.2% in patients over 60-years old. The incidence of ≥ 75% stenosis and multiple stenosis increased with age, however it should be noticed there were 18.93% for ≥ 75% stenosis and 19.52% for multiple stenosis in patients under 40 years old.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Mackay J, Mensah GA, Mendis S, Greenlund K, World Health Organization (2004) The atlas of heart disease and stroke. Geneva: WHO. http://www.who.int/cardiovascular_diseases/resources/atlas/en/

  2. Wang H, Steffen LM, Jacobs DR, Zhou X, Blackburn H, Berger AK, Filion KB, Luepker RV (2011) Trends in cardiovascular risk factor levels in the Minnesota Heart Survey (1980–2002) as compared with the National Health and Nutrition Examination Survey (1976–2002): a partial explanation for Minnesota’s low cardiovascular disease mortality?. Am J Epidemiol 173:526–538. doi:10.1093/aje/kwq367

    Article  PubMed  PubMed Central  Google Scholar 

  3. (2012) New data on cardiovascular interventions in China reported. Cardiovasc Diagn Ther 2(2):178–180. doi:10.3978/j.issn.2223-3652.2012.03.01

  4. Chen WW, Gao RL, Liu LS et al (2015) Summary of report on cardiovascular diseases in China. 2014. Chin Circ J 30(7):617–622 (in Chinese)

    Google Scholar 

  5. Jiang G, Wang D, Li W, Pan Y, Zheng W, Zhang H, Sun YV (2012) Coronary heart disease mortality in China: age, gender, and urban-rural gaps during epidemiological transition. Rev Panam Salud Publica 31(4):317–324

    Article  PubMed  Google Scholar 

  6. Sbarouni E, Voudris V, Georgiadou P, Hamilos M, Steg PG, Fox KM (2014) On behalf of the Greek CLARIFY investigators (see Appendix). Clinical presentation and management of stable coronary artery disease: insights from the international prospective CLARIFY registry-results from the Greek national cohort. Hellenic J Cardiol 55(6):442–447

    PubMed  Google Scholar 

  7. Jiang SS, Lü L, Juergens C, Gong JB, Wang LJ, Peng YP, Xu DJ, Huang ZY (2007) Coronary artery lesion comparison between Chinese and Australian patients with coronary artery disease. Zhonghua Xin Xue Guan Bing Za Zhi 35(5):447–450 (in Chinese)

    PubMed  Google Scholar 

  8. Dai J, Chen R, Meng X, Yang C, Zhao Z, Kan H (2015) Ambient air pollution, temperature and out-of-hospital coronary deaths in Shanghai, China. Environ Pollut 203:116–121. doi:10.1016/j.envpol.2015.03.050

    Article  CAS  PubMed  Google Scholar 

  9. Scanlon PJ, Faxon DP, Audet AM et al (1999) ACC/AHA guidelines for coronary angiography: executive summary and recommendations. A report of the American College of Cardiology/American Heart Association Task on Practice Guidelines (Committee on Coronary Angiography) developed in collaboration with the Society for Cardiac Angiography and interventions. Circulation 99(17):2345–2357

    Article  CAS  PubMed  Google Scholar 

  10. Fang YQ, Yang CM, Wang XK, Zhou L, Wang HY, Zeng CY (2011) Feasibility and application of single 5F multipurpose catheter in coronary and peripheral angiography via a transradial approach. Int J Cardiol 151(9):182–186. doi:10.1016/j.ijcard.2010.05.014

    Article  PubMed  Google Scholar 

  11. American Heart Association (2001) 2002 heart and stroke statistical update. American Heart Association, Dallas

    Google Scholar 

  12. Falk E, Shah PK, Fuster V (1995) Coronary plaque disruption. Circulation 92(3):657–671

    Article  CAS  PubMed  Google Scholar 

  13. Habib PJ, Green J, Butterfield RC, Kuntz GM, Murthy R, Kraemer DF, Percy RF, Miller AB, Strom JA (2013) Association of cardiac events with coronary artery disease detected by 64-slice or greater coronary CT angiography: a systematic review and meta-analysis. Int J Cardiol 169(2):112–120. doi:10.1016/j.ijcard.2013.08.096

    Article  PubMed  Google Scholar 

  14. Patel MR, Peterson ED, Dai D, Brennan JM, Redberg RF, Anderson HV, Brindis RG, Douglas PS (2010) Low diagnostic yield of elective coronary angiography. N Engl J Med 362(10):886–895. doi:10.1056/NEJMoa0907272

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  15. Hu SS, Kong LZ, Gao RL, Zhu ML, Wang W, Wang YJ, Wu ZS, Chen WW, Liu MB, Editorial Board (2012) Outline of the report on cardiovascular disease in China, 2010. Biomed Environ Sci 25(3):251–256. doi:10.3967/0895-3988.2012.03.001

    PubMed  Google Scholar 

  16. Wang W, Hu SS, Kong LZ, Gao RL, Zhu ML, Wang WY, Wu ZS, Chen WW, Yang JG, Ma LY, Liu MB, Editorial Board (2014) Summary of report on cardiovascular diseases in China, 2012. Biomed Environ Sci 27(7):552–558. doi:10.3967/bes2014.085

    PubMed  Google Scholar 

  17. Li H, Ge J (2015) Cardiovascular diseases in China: current status and future perspectives. IJC Heart Vasculature 6:25–31

    Article  PubMed  Google Scholar 

  18. Liu J, Zhao D, Liu J, Qi Y, Sun J, Wang Y, Wang W (2014) Changes in the diagnosis and treatment of hospitalized patients with acute coronary syndrome from 2006 to 2012 in China. Zhonghua Xin Xue Guan Bing Za Zhi 42(11):957–962 (in Chinese)

    PubMed  Google Scholar 

  19. Abdulla J, Asferg C, Kofoed KF (2011) Prognostic value of absence or presence of coronary artery disease determined by 64-slice computed tomography coronary angiography a systematic review and meta-analysis. Int J Cardiovasc Imaging 27(3):413–420. doi:10.1007/s10554-010-9652-x

    Article  PubMed  Google Scholar 

  20. Wassef NZ, Ehtisham J, Petal N, Shaukat N (2014) Prognosis of troponin-positive patients with non-obstructive coronary artery disease. Cardiol Ther 3(1–2):41–51. doi:10.1007/s40119-014-0027-6

    Article  PubMed  PubMed Central  Google Scholar 

  21. Segev A, Beigel R, Goitein O, Brosh S, Oiero D, Konen E, Hod H, Matetzky S (2012) Non-obstructive coronary artery disease upon multi-detector computed tomography in patients presenting with acute chest pain—results of an intermediate term follow-up. Eur Heart J Cardiovasc Imaging 13(2):169–173. doi:10.1093/ejechocard/jer189

    Article  PubMed  Google Scholar 

Download references

Funding

This study was funded by National Nature Science Foundation of China (81570312).

Author information

Authors and Affiliations

Authors

Corresponding authors

Correspondence to Chunyu Zeng or Yuqiang Fang.

Ethics declarations

Conflict of interest

All authors declare that there is no conflict of interest.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed consent

Informed consent was obtained from all individual participants included in the study.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Yin, Z., Zeng, C., Zhang, X. et al. The characteristics of coronary stenosis in 11,267 patients from Southwest China: a retrospective study. J Thromb Thrombolysis 45, 142–150 (2018). https://doi.org/10.1007/s11239-017-1568-z

Download citation

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11239-017-1568-z

Keywords

Navigation