Table 4 Basic knowledge units detected by using cue words ‘conflicting’, ‘controversial’, and ‘contradictory’ within one sentence

From: Towards medical knowmetrics: representing and computing medical knowledge using semantic predications as the knowledge unit and the uncertainty as the knowledge context

Date of Publication Knowledge source (PMID-claims) Basic knowledge unit (S-P-O triple) Knowledge status (uncertainty)
1999 Oct 10,528,024.ab.1 BACKGROUND: Higher blood levels of alpha-tocopherol, the predominant form of vitamin E, have been associated in some studies with a reduced risk of lung cancer, but other studies have yielded conflicting results Vitamin E-DISRUPTS-Malignant neoplasm of lung conflicting
2008 Jan 18,187,393.ab.1 BACKGROUND: Prior studies indicate that use of aspirin or other nonsteroidal anti-inflammatory drugs (NSAID) is associated with a decreased risk of non-small cell lung cancer (NSCLC); however, results have been contradictory in part because of variation in study design Aspirin-PREVENTS-Non-Small Cell Lung Carcinoma contradictory
2009 Sep 19,144,444.ab.1 OBJECTIVE: Whether platinum plus gemcitabine or vinorelbine are equally effective in the treatment of advanced non-small-cell lung cancer (NSCLC) is still controversial, a meta-analysis was performed to compare the gemcitabine plus platinum Gemcitabine, vinorelbine-TREATS- Non-Small Cell Lung Carcinoma controversial
2011 Nov 22,073,154.ab.1 BACKGROUND: Selenium is a natural health product widely used in the treatment and prevention of lung cancers, but large chemoprevention trials have yielded conflicting results Selenium-PREVENTS-Malignant neoplasm of lung conflicting
2014 Feb 24,372,368.ab.1 PURPOSE: Our knowledge on bronchoalveolar lavage (BAL) of methotrexate-induced pneumonitis (MTX-P) is fragmentary and based on data that are sometimes apparently conflicting Methotrexate-CAUSES-Pneumonia conflicting
2014 Oct* 24,989,113.ab.2 Impacts on the catalytic activity of the CYP1B1 enzyme, as well as an association of the Leu432Val polymorphism with the risk of lung cancer, have been described; however, the results remain controversial Cytochrome-P-450-CYP1B1 PREDISPOSES Malignant neoplasm of lung controversial
2014 Aug 25,016,505.ab.1 PURPOSE: Evidence on the benefits of combining celecoxib, a cyclooxygenase-2 inhibitor, in treating advanced cancer is still controversial Celecoxib-TREATS-Advanced cancer controversial
2014 Jul 25,029,199.ab.1 BACKGROUND: Since efficacy and safety of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR-TKIs) versus chemotherapy in the treatment of patients with pretreated advanced non-small cell lung cancer (NSCLC) remain controversial, we performed a meta-analysis to compare them Epidermal growth factor receptor inhibitor (product) –TREATS- Non-Small Cell Lung Carcinoma controversial
2014 Mar 25,818,741.ab.1 BACKGROUND: The extent of the benefit of gefitinib in the treatment of advanced nonsmall-cell lung cancer (NSCLC) is till controversial, when compared with docetaxel Gefitinib-TREATS-Non-Small Cell Lung Carcinoma controversial
2015 Nov 26,548,932.ab.1 BACKGROUND: The extent of the benefit of erlotinib in the treatment of advanced nonsmall-cell lung cancer (NSCLC) is still controversial when compared with docetaxel Erlotinib-TREATS-Non-Small Cell Lung Carcinoma controversial
2016 Aug 27,305,276.ab.1 BACKGROUND/AIM: The utility of pulmonary function testing (PFT) to detect bleomycin-induced pneumonitis is controversial Bleomycin-CAUSES-Pneumonia controversial
2017 Apr 28,150,074.ab.1 Background The efficacy and safety of bevacizumab in elderly patients with non-small cell lung cancer remain controversial Bevacizumab-TREATS-Non-Small Cell Lung Carcinoma controversial
2017 Jun* 28,502,040.ab.3 Whether UGT1A1*6 and UGT1A1*28 are associated with IRI-induced neutropenia, diarrhea and IRI-based chemotherapy tumor response (TR) in Asians with lung cancer remains controversial Irinotecan-CAUSES-Leukopenia controversial
2017 Jun 28,643,733.ab.1 BACKGROUND: The use of cisplatin (Cis) versus carboplatin (Carb) in the treatment of advanced nonsmall cell lung cancer (NSCLC) is controversial Cisplatin-TREATS-Non-Small Cell Lung Carcinoma controversial
2017 Jun 28,643,733.ab.1 BACKGROUND: The use of cisplatin (Cis) versus carboplatin (Carb) in the treatment of advanced nonsmall cell lung cancer (NSCLC) is controversial Carboplatin-TREATS-Non-Small Cell Lung Carcinoma controversial
  1. * Not in the scope of the present study