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Russian Journal of Organic Chemistry

, Volume 41, Issue 12, pp 1824–1835 | Cite as

Synthesis of New Derivatives of Protoporphyrin IX and Chlorophyll a

  • V. Yu. Pavlov
  • I. O. Konstantinov
  • G. V. Ponomarev
  • V. P. Timofeev
  • B. G. Kimel'
Article

Abstract

The vinyl groups in protoporphyrin IX and chlorophyll a derivatives were selectively transformed into hydroxymethyl and acetoxymethyl substituents. The reactivities of β-hydroxymethyl and β-acetoxymethyl groups in porphyrins and chlorins toward nucleophilic reagents were compared for the first time using the reaction with acetylacetone as an example. Peripheral acetylacetone moieties in porphyrins and chlorins were shown to be promising as building blocks for generation of exo heterocyclic structures.

Keywords

Chlorophyll Organic Chemistry Chlorin Vinyl Porphyrin 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© MAIK "Nauka/Interperiodica" 2005

Authors and Affiliations

  • V. Yu. Pavlov
    • 1
    • 2
  • I. O. Konstantinov
    • 3
  • G. V. Ponomarev
    • 3
  • V. P. Timofeev
    • 4
  • B. G. Kimel'
    • 5
  1. 1.Faculty of ChemistryMoscow State UniversityMoscowRussia
  2. 2.Lomonosov Moscow State Academy of Chemical TechnologyMoscowRussia
  3. 3.“Orekhovich Research Institute” State EnterpriseRussian Academy of Medical SciencesMoscowRussia
  4. 4.Engel'gardt Institute of Molecular BiologyRussian Academy of SciencesMoscowRussia
  5. 5.Zelinskii Institute of Organic ChemistryRussian Academy of SciencesMoscowRussia

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