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Russian Journal of Organic Chemistry

, Volume 41, Issue 9, pp 1354–1358 | Cite as

3-Methylidene-2,4-dioxo-4-pentafluorophenylbutanoates in the Synthesis of Heterocycles

  • A. S. Fokin
  • Ya. V. Burgart
  • V. I. Saloutin
  • O. N. Chupakhin
Article

Abstract

3-Ethoxy- and 3-arylaminomethylidene-2,4-dioxo-4-pentafluorophenylbutanoates undergo cyclization by the action of hydrazine hydrate and phenylhydrazine to give ethyl 4-pentafluorobenzoylpyrazole-5-carboxylates. The reaction of 3-ethoxymethylidene-2,4-dioxo-4-pentafluorophenylbutanoate with o-phenylene-diamine leads to formation of 3-[2-(2-aminophenylamino)-1-pentafluorobenzoylethenyl]-1,2-dihydroquinoxa-lin-2-one. 3-Arylaminomethylidene-2,4-dioxo-4-pentafluorophenylbutanoates react with o-phenylenediamine to afford 3-(1-aryl-5,6,7,8-tetrafluoro-4-oxo-1,4-dihydroquinolin-3-yl)-1,2-dihydroquinoxalin-2-ones and/or 3-(2-arylamino-1-pentafluorobenzoylethenyl)-1,2-dihydroquinoxalin-2-ones.

Keywords

Ethyl Hydrate Organic Chemistry Hydrazine Hydrazine Hydrate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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REFERENCES

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Copyright information

© MAIK "Nauka/Interperiodica" 2005

Authors and Affiliations

  • A. S. Fokin
    • 1
  • Ya. V. Burgart
    • 1
  • V. I. Saloutin
    • 1
  • O. N. Chupakhin
    • 1
  1. 1.Institute of Organic Synthesis, Ural DivisionRussian Academy of SciencesYekaterinburgRussia

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