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Polysiloxane based on hydroxyl-containing monomer. Preparation, properties and biomedical application

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Abstract

A method for synthesis of hyperbranched polysiloxane based on N-methyl-N-(2,3,4,5,6-pentahydroxyhexyl)-N’-(3-triethoxysilylpropyl)urea is proposed. In water, the polymer forms nanoparticles capable of holding low soluble luminophores (tetracyanotetraarylporphyrazines) due to non-covalent interaction. Intensively luminescent stable aqueous suspensions based on non-toxic siloxane nanoparticles can be used in bioimaging.

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Authors and Affiliations

  1. Razuvaev Institute of Organometallic Chemistry, Russian Academy of Sciences, 49 ul. Tropinina, 603950, Nizhni Novgorod, Russian Federation

    T. S. Lyubova, S. A. Lermontova, E. Yu. Ladilina & L. G. Klapshina

  2. Lobachevsky State University of Nizhny Novgorod, 23 prosp. Gagarina, 603950, Nizhny Novgorod, Russian Federation

    N. S. Zakharycheva & E. A. Zakharychev

Authors
  1. T. S. Lyubova
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  2. N. S. Zakharycheva
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  3. E. A. Zakharychev
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  4. S. A. Lermontova
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  5. E. Yu. Ladilina
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  6. L. G. Klapshina
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Corresponding author

Correspondence to E. Yu. Ladilina.

Additional information

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 1075–1080, May, 2019.

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Lyubova, T.S., Zakharycheva, N.S., Zakharychev, E.A. et al. Polysiloxane based on hydroxyl-containing monomer. Preparation, properties and biomedical application. Russ Chem Bull 68, 1075–1080 (2019). https://doi.org/10.1007/s11172-019-2522-3

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  • DOI: https://doi.org/10.1007/s11172-019-2522-3

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