Abstract
Quadricyclane derivatives are shown for the first time to be promising for application as anticancer drugs. The efficiency of such cage compounds is mainly due to thermal action on cancer cells resulting from a C—C bond cleavage in quadricyclane on exposure to catalytic amounts of cisplatin Pt ions.
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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 1036–1040, May, 2019.
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Dzhemilev, U.M., Akhmetov, A.R., Khuzin, A.A. et al. A new original approach to the design of anticancer drugs based on energy-rich quadricyclanes. Russ Chem Bull 68, 1036–1040 (2019). https://doi.org/10.1007/s11172-019-2516-1
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DOI: https://doi.org/10.1007/s11172-019-2516-1