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Comparative evaluation of antioxidant activity of 2-alkyl-4-methylphenols and their 6-n-octylaminomethyl derivatives

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Abstract

A series of 2-alkyl-4-methyl-6-n-octylaminomethylphenols (where alkyl is methyl or tert-butyl group, or terpene substituent) was synthesized. A comparative evaluation of the antioxidant properties of the starting alkyl- and terpenylphenols and their Mannich bases was carried out using in vitro assays. Structural features providing high antioxidant activity of these compounds were revealed.

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Authors and Affiliations

  1. Institute of Chemistry, Komi Scientific Center, Ural Branch of the Russian Academy of Sciences, 48 ul. Pervomaiskaya, 167000, Syktyvkar, Russian Federation

    E. V. Buravlev & I. V. Fedorova

  2. Institute of Biology, Komi Scientific Center, Ural Branch of the Russian Academy of Sciences, 28 ul. Kommunisticheskaya, 167982, Syktyvkar, Russian Federation

    O. G. Shevchenko

Authors
  1. E. V. Buravlev
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  2. I. V. Fedorova
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  3. O. G. Shevchenko
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Corresponding author

Correspondence to E. V. Buravlev.

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Dedicated to Corresponding Member of the Russian Academy of Sciences A. V. Kutchin on the occasion of his 70th birthday.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 0985–0992, May, 2019.

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Buravlev, E.V., Fedorova, I.V. & Shevchenko, O.G. Comparative evaluation of antioxidant activity of 2-alkyl-4-methylphenols and their 6-n-octylaminomethyl derivatives. Russ Chem Bull 68, 985–992 (2019). https://doi.org/10.1007/s11172-019-2508-1

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  • DOI: https://doi.org/10.1007/s11172-019-2508-1

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