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Pro- and antioxidant properties of uracil derivatives

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Russian Chemical Bulletin Aims and scope

Abstract

The review summarizes data on pro- and antioxidant properties of uracil derivatives comprising an important group of pharmacologically active compounds. The presence of OH or NH2 groups at position 5 of the uracil ring was shown to be essential for these compounds to have both antioxidant and prooxidant properties. The mechanism of pro- and antioxidant action is discussed.

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Authors and Affiliations

  1. Ufa Institute of Chemistry, Ufa Federal Research Centre, Russian Academy of Sciences, 71 prosp. Oktyabrya, 450054, Ufa, Russian Federation

    Yu. I. Murinov, S. A. Grabovskii & N. N. Kabal’nova

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  1. Yu. I. Murinov
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  2. S. A. Grabovskii
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  3. N. N. Kabal’nova
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Correspondence to Yu. I. Murinov.

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Based on the materials of the IV Interdisciplinary Symposium on Medicinal, Organic, Biological Chemistry and Pharmaceutics (MOBI-ChemPharma 2018) (September 23–26, 2018, Novyi Svet, Crimea).

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 5, pp. 0946–0954, May, 2019.

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Murinov, Y.I., Grabovskii, S.A. & Kabal’nova, N.N. Pro- and antioxidant properties of uracil derivatives. Russ Chem Bull 68, 946–954 (2019). https://doi.org/10.1007/s11172-019-2505-4

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  • DOI: https://doi.org/10.1007/s11172-019-2505-4

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