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Mixed systems based on the cationic surfactant with a butyl carbamate fragment and nonionic surfactant Tween 80: Aggregation behavior and solubilization properties

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Abstract

Mixed micelles are formed in the binary compositions based on the cationic surfactant functionalized by the butyl carbamate fragment and nonionic surfactant Tween 80 in aqueous solutions. The aggregation parameters of the formed micelles (critical micelle concentration, size, and surface potential) depend on the component ratio in the system. The solubilization effect of individual and mixed micelles on the drugs of the heterocyclic series, indomethacin and 1-[5-(4-chlorophenyl)-3-phenylpyrrol-2-yl)]benzimidazol-2(3H)-one, was quantitatively characterized.

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Authors and Affiliations

  1. A. E. Arbuzov Institute of Organic and Physical Chemistry – Subdivision of the Federal Reseach Center “Kazan Scientific Center of the Russian Academy of Sciences,”, 8 ul. Akad. Arbuzova, 420088, Kazan, Russian Federation

    A. B. Mirgorodskaya, R. A. Kushnazarova, A. Yu. Shcherbakov, S. S. Lukashenko, N. A. Zhukova, V. A. Mamedov & L. Ya. Zakharova

  2. Kazan National Research Technological University, 68 ul. K. Marksa, 420015, Kazan, Russian Federation

    V. A. Mamedov, L. Ya. Zakharova & O. G. Sinyashin

Authors
  1. A. B. Mirgorodskaya
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  2. R. A. Kushnazarova
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  3. A. Yu. Shcherbakov
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  4. S. S. Lukashenko
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  5. N. A. Zhukova
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  6. V. A. Mamedov
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  7. L. Ya. Zakharova
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  8. O. G. Sinyashin
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Corresponding author

Correspondence to A. B. Mirgorodskaya.

Additional information

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 11, pp. 1992–1996, November, 2018.

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Mirgorodskaya, A.B., Kushnazarova, R.A., Shcherbakov, A.Y. et al. Mixed systems based on the cationic surfactant with a butyl carbamate fragment and nonionic surfactant Tween 80: Aggregation behavior and solubilization properties. Russ Chem Bull 67, 1992–1996 (2018). https://doi.org/10.1007/s11172-018-2319-9

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  • DOI: https://doi.org/10.1007/s11172-018-2319-9

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