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Russian Chemical Bulletin

, Volume 64, Issue 5, pp 1125–1133 | Cite as

Synthesis of mono- and di-O-sulfates of spacer-armed lactose

  • M. A. Sablina
  • A. B. Tuzikov
  • T. V. Ovchinnikova
  • I. V. Mikhura
  • N. V. Bovin
Full Articles

Abstract

A series of spacer-armed lactose derivatives with one or two O-sulfo groups in various positions, namely, 6-O-Su-Lac, 3´,6-O-Su2-Lac, 6´-O-Su-Lac, 6,6´-O-Su2-Lac, and 3´-O-Su-Lac (Su = SO3H), was synthesized starting from the same precursor. All sulfated disaccharides were obtained in the form of 2-aminoethyl glycosides.

Keywords

lactose O-sulfates sulfation sulfated glycanssynthesis synthesis 

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • M. A. Sablina
    • 1
  • A. B. Tuzikov
    • 1
  • T. V. Ovchinnikova
    • 1
  • I. V. Mikhura
    • 1
  • N. V. Bovin
    • 1
  1. 1.M. M. Shemyakin and Yu. A. Ovchinnikov Institute of Bioorganic ChemistryRussian Academy of SciencesMoscowRussian Federation

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