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Russian Chemical Bulletin

, Volume 64, Issue 5, pp 1049–1052 | Cite as

Fluorination of aromatic compounds with xenon difluoride in the presence of boron trifluoride etherate

  • A. E. Fedorov
  • A. A. Zubarev
  • V. Yu. Mortikov
  • L. A. Rodinovskaya
  • A. M. Shestopalov
Full Articles

Abstract

Fluorination of benzene with the XeF2—BF3•Et2O system in acetonitrile at low temperatures affords fluorobenzene in 18% yield, the conversion of benzene being 92%. The rest products are di-, tri-, tetra-, and polyphenyls with different fluorination pattern. Toluene and chloro- and bromobenzenes are fluorinated predominantly at the ortho and para positions. Fluorination of 4-nitroanisole affords 2-fluoro-4-nitroanisole in 73% yield.

Keywords

xenon difluoride boron trifluoride etherate fluorobenzene fluoroarenes organofluorine compounds 

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Copyright information

© Springer Science+Business Media New York 2015

Authors and Affiliations

  • A. E. Fedorov
    • 1
  • A. A. Zubarev
    • 1
  • V. Yu. Mortikov
    • 1
  • L. A. Rodinovskaya
    • 1
  • A. M. Shestopalov
    • 1
  1. 1.N. D. Zelinsky Insitute of Organic ChemistryRussian Academy of SciencesMoscowRussian Federation

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