Fluorination of aromatic compounds with xenon difluoride in the presence of boron trifluoride etherate
Fluorination of benzene with the XeF2—BF3•Et2O system in acetonitrile at low temperatures affords fluorobenzene in 18% yield, the conversion of benzene being 92%. The rest products are di-, tri-, tetra-, and polyphenyls with different fluorination pattern. Toluene and chloro- and bromobenzenes are fluorinated predominantly at the ortho and para positions. Fluorination of 4-nitroanisole affords 2-fluoro-4-nitroanisole in 73% yield.
Keywordsxenon difluoride boron trifluoride etherate fluorobenzene fluoroarenes organofluorine compounds
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