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Russian Chemical Bulletin

, Volume 63, Issue 5, pp 1153–1158 | Cite as

Synthesis of 2-(4-methyl-1,3-thiazol-5-yl)ethyl esters of acridone carboxylic acids and evaluation of their antibacterial activity

  • Yu. D. Markovich
  • T. N. Kudryavtseva
  • K. V. Bogatyrev
  • P. I. Sysoev
  • L. G. Klimova
  • G. V. Nazarov
Full Articles

Abstract

2-(4-Methyl-1,3-thiazol-5-yl)ethyl acridone carboxylates were synthesized by the transesterification of the corresponding butyl esters. The kinetic characteristics of these reactions were determined, and the antimicrobial activity of a number of reaction products was investigated.

Key words

esters of acridone carboxylic acids 5-(2-hydroxyethyl)-4-methylthiazole transesterification rate constants antibacterial activity 

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Copyright information

© Springer Science+Business Media New York 2014

Authors and Affiliations

  • Yu. D. Markovich
    • 1
  • T. N. Kudryavtseva
    • 1
  • K. V. Bogatyrev
    • 1
  • P. I. Sysoev
    • 1
  • L. G. Klimova
    • 2
  • G. V. Nazarov
    • 1
  1. 1.Kursk State UniversityKurskRussian Federation
  2. 2.Kursk State Medical UniversityKurskRussian Federation

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