Skip to main content
Log in

Colloid-chemical aspects of protein crystallization

  • Reviews
  • Published:
Russian Chemical Bulletin Aims and scope

Abstract

Problems and prospects of the crystallization of water-soluble and membrane proteins are discussed. The main focus is on colloid-chemical aspects of crystallization processes and the use of surfactants and various structured dispersions (surfactant-based gels and lyotropic phases). Advantages of the protein crystallization on solid supports of different nature, including biopolymer supports, are considered. Apparently, we are witnesses to the rise of a new field, nanocrystallography, dealing with the determination of protein structures from the investigation of nanocrystals.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. T. Blundell, L. Johnson, Protein Crystallography, Academic Press, 1976.

    Google Scholar 

  2. K. A. Dill, J. L. MacCallum, Science, 2012, 338, 1041.

    Google Scholar 

  3. I. Schmidt-Krey, Methods, 2007, 41, 417.

    CAS  Google Scholar 

  4. T. V. M Ochi, V. Bolanos-Garcia, A. Stojanoff, A. Moreno, Prog. Biophys. Mol. Biol., 2009, 101, 56.

    CAS  Google Scholar 

  5. P. Savitsky, J. Bray, C. D. O. Cooper, B. D. Marsden, P. Mahajan, N. A. Burgess-Brown, O. Gileadi, J. Struct. Biol., 2010, 172, 3.

    CAS  Google Scholar 

  6. I. Schmidt-Krey, J. L. Rubinstein, Micron, 2011, 42, 107.

    CAS  Google Scholar 

  7. N. Coudray, G. Hermann, D. Caujolle-Bert, A. Karathanou, F. Erne-Brand, J.-L. Buessler, P. Dauma, J. M. Plitzko, M. Chami, U. Mueller, H. Kihl, J.-P. Urban, A. Engel, H.-W. Remigy, J. Struct. Biology, 2011, 173, 365.

    CAS  Google Scholar 

  8. O. S. Sokolova, Dr. Sc. (Biol.) Thesis, Moscow, 2012 (in Russian).

  9. V. M. Bolanos-Garcia, N. E. Chayen, Prog. Biophys. Mol. Biol., 2009, 101, 3.

    CAS  Google Scholar 

  10. N. E. Chayen, Curr. Opin. Struct. Biol., 2004, 14. 577.

    Google Scholar 

  11. S. K. Basu, C. P. Govardhan, C. W. Jung, A. L. Margolin, Expert Opin. Biol. Ther., 2004, 4, 301.

    CAS  Google Scholar 

  12. G. Palazzo, Curr. Opin. Colloid Interface Sci., 2006, 11, 65.

    CAS  Google Scholar 

  13. A. C. Dumetz, A. M. Chockla, E.W. Kaler, A. M. Lenhoff, Biophys. J., 2008, 94, 570.

    CAS  Google Scholar 

  14. S. P. Rozhkov, J. Cryst. Growth, 2004, 273, 266.

    CAS  Google Scholar 

  15. S. P. Rozhkov, A. S. Goryunov, Biophys. Chem., 2010, 151, 22.

    CAS  Google Scholar 

  16. A. Schaper, Y. Georgalis, P. Umbach, J. Raptis, W. Saenger, Chem. Phys., 1997, 106, 8587.

    CAS  Google Scholar 

  17. N. Asherie, Methods, 2004, 34, 266.

    CAS  Google Scholar 

  18. O. Galkin, P. Vekilov, J. Phys. Chem., 1999, 103, 41.

    Google Scholar 

  19. Y. G. Kuznestov, A. J. Malkin, A. McPherson, J. Cryst. Growth, 2001, 232, 30.

    Google Scholar 

  20. S. Gorti, J. Konnert, E. Forsythe, M. Pusey, Cryst. Growth Design, 2005, 5, 535.

    CAS  Google Scholar 

  21. C. N. Nanev, Cryst. Growth Design, 2007, 7, 1533.

    CAS  Google Scholar 

  22. A. A. Chernov, J. Struct. Biology, 2003, 142, 3.

    CAS  Google Scholar 

  23. J. P. K. Doye, W. C. K. Poon, Curr. Opin. Colloid Interface Sci., 2006, 11, 40.

    CAS  Google Scholar 

  24. D. R. Davies, D. M. Segal, Methods Enzymol., 1971, 22, 266.

    Google Scholar 

  25. J. Nowakowski, C. Cronin, D. McRee, M. Knuth, C. Nelson, N. Pavletich, Protein Structure, 2002, 10, 1659.

    CAS  Google Scholar 

  26. G. Cingolani, S. Moore, P. Prevelige, Jr., J. Johnson, J. Struct. Biology, 2002, 139, 46.

    CAS  Google Scholar 

  27. N. Chayen, Prog. Biophys. Mol. Biol., 2005, 88, 329.

    CAS  Google Scholar 

  28. D. Tsekova, D. Williams, J. Heng, Chemical Engineering Science, 2012, 77, 201.

    CAS  Google Scholar 

  29. B. Lorber, M. Adrian, J. Witz, M. Erhardt, J. Harris, Micron, 2008, 39, 431.

    CAS  Google Scholar 

  30. V. N. Izmailova, G. P. Yampol’skaya, B. D. Summ, Poverkhnostnye yavleniya v belkovykh sistemakh [Surface Phenomena in Protein Systems], Khimiya, Moscow, 1988, p. 240 (in Russian).

    Google Scholar 

  31. V. N. Izmailova, G. P. Yampolskaya, in Studies in Interface Science. 7. Proteins at Liquid Interfaces, Eds D. Mobius, R. Miller, Elsevier, 1998, 103.

  32. Fommer, S. A. Dubreuil, D. Lair, T. Duc, J. Valleton, Langmuir, 1997, 13, 791.

    Google Scholar 

  33. M. Dezi, P-F. Fribourg, A. Di Cicco, J.-M. Jault, M. Chami, D. Levy, J. Struct. Biol., 2011, 174, 307.

    CAS  Google Scholar 

  34. N. Coudray, G. Hermann, D. Caujolle-Bert, A. Karathanou, F. Erne-Brand, J.-L. Buessler, P. Daum, J. M. Plitzko, M. Chami, U. Mueller, H. Kihl, J.-P. Urban, A. Engel, H.-W. Remigy, J. Struct. Biol., 2011, 173, 365.

    CAS  Google Scholar 

  35. R. Henderson, P. N. T. Unwin, Nature, 1975, 257, 28.

    CAS  Google Scholar 

  36. R. Henderson, J. M. Baldwin, T. A. Ceska, F. Zemlin, E. Beckman, K. H. Downing, J. Mol. Biol., 1990, 213, 899.

    CAS  Google Scholar 

  37. W. Kohlbrandt, D. N. Wang, Y. Fujiyoshi, Nature, 1994, 367, 614.

    Google Scholar 

  38. K. Murata, K. Mitsuoka, T. Hirai, T. Walz, P. Agre, J. B. Heymann, A. Engel, Y. Fujiyoshi, Nature, 2000, 407, 599.

    CAS  Google Scholar 

  39. G. Ren, V. S. Reddy, A. Cheng, P. Melnyk, A. K. Mitra, Proc. Natl. Acad. Sci. USA, 2001, 98, 1398.

    CAS  Google Scholar 

  40. A. Miyazawa, Y. Fujiyoshi, N. Unwin, Nature, 2003, 423, 949.

    CAS  Google Scholar 

  41. T. Gonen, P. Sliz, J. Kistler, Y. Cheng, T. Walz, Nature, 2004, 429, 193.

    CAS  Google Scholar 

  42. Y. Hiroaki, K. Tani, A. Kamegawa, N. Gyobu, K. Nishikawa, H. Suzuki, T. Walz, S. Sasaki, K. Mitsuoka, K. Kimura, A. Mizoguchi, Y. Fujiyoshi, J. Mol. Biol., 2006, 355, 628.

    CAS  Google Scholar 

  43. E. Nogales, S. G. Wolf, K. H. Downing, Nature, 1998, 391, 199.

    CAS  Google Scholar 

  44. J. Lowe, H. Li, K. H. Downing, E. Nogales, J. Mol. Biol., 2001, 313, 1045.

    CAS  Google Scholar 

  45. T. Gonen, Y. Cheng, P. Sliz, Y. Hiroaki, Y. Fujiyoshi, S. C. Harrison, T. Walz, Nature, 2005, 438, 633.

    CAS  Google Scholar 

  46. I. Iacovache, M. Biasini, J. Kowal, W. Kukulski, M. Chami, F. G. van der Goot, A. Engel, H.-W. Remigy, J. Struct. Biol., 2010, 169, 370.

    CAS  Google Scholar 

  47. G. Signorell, T. Kaufmann, W. Kukulski, A. Engel, H.-W. Remigy, J. Struc. Biol., 2007, 157, 321.

    CAS  Google Scholar 

  48. B. Lorber, C. Sauter, A. Théobald-Dietrich, A. Moreno, P. Schellenberge, M.-C. Robert, B. Capelle, S. Sanglier, N. Potier, R. Giegé, Prog. Biophys. Mol. Biol., 2009, 101, 13.

    CAS  Google Scholar 

  49. A. Kadria, B. Lorbera, G. Jenner, R. Giegé, J. Cryst. Growth, 2002, 245, 109.

    Google Scholar 

  50. G. P. Yampol’skaya, A. A. Elenskii, N. V. Pan’kina, B. N. Tarasevich, V. G. Kulichikhin, Kolloid. Zh., 2009, 71, 275 [Colloid. J. (Engl. Transl.), 2009, 71, 275].

    Google Scholar 

  51. L. Wang, X.-Y. Liu, Biophys. J., 2008, 95, 5931.

    CAS  Google Scholar 

  52. J. Gutenwik, B. Nilsson, A. Axelsson, J. Chromatography A, 2004, 1048, 161.

    CAS  Google Scholar 

  53. C. Charron, M.-C. Robert, B. Capelle, A. Kadria, G. Jenner, R. Giege, B. Lorber, J. Cryst. Growth, 2002, 245, 321.

    CAS  Google Scholar 

  54. K. Nakamura, Y. Sora, H. Y. Yoshikawa, Y. Hosokawa, R. Murai, H. Adachi, Y. Mori, T. Sasaki, H. Masuhara, Appl. Surf. Sci., 2007, 253, 6425.

    CAS  Google Scholar 

  55. H. Yoshikawa, R. Murai, S. Sugiyama, G. Sazaki, T. Kitatani, Y. Takahashi, H. Adachi, H. Matsumura, S. Murakami, T. Inoue, K. Takano, Y. Mori, J. Cryst. Growth, 2009, 311, 956.

    CAS  Google Scholar 

  56. H. Hasenaka, S. Sugiyama, M. Hirosea, N. Shimizu, T. Kitatani, Y. Takahashi, H. Adachi, K. Takano, S. Murakami, T. Inoue, Y. Mori, H. Matsumura, J. Cryst. Growth, 2009, 312, 73.

    CAS  Google Scholar 

  57. N. M. Zadymova, G. P. Yampol’skaya, L. Yu. Filatova, Kolloid. Zh., 2006, 68, 187 [N. M. Zadymova, G. P. Yampol’skaya, L. Y. Filatova, Colloid. J. (Engl. Transl.), 2006, 68, 187].

    Google Scholar 

  58. Zh. K. Angarskaa, A. A. Elenskyi, G. P. Yampolskaya, K. D. Tachev, Colloids Surfaces A: Physicochem. Eng. Aspects, 2011, 382, 102.

    Google Scholar 

  59. K. Holmberg, B. Jonsson, B. Lindman, Surfactants and Polymers in Aqueous Solution, JohnWiley & Sons, 2nd Ed. 2004.

    Google Scholar 

  60. P. Spicer, Curr. Opin. Colloid Interface Sci., 2005, 10, 274.

    CAS  Google Scholar 

  61. R. Gomati, N. Bouguerra, A. Gharbi, Physica B, 2002, 322, 262.

    CAS  Google Scholar 

  62. M. Berni, C. J. Lawrence, D. Machin, Adv. Colloid Interface Sci., 2002, 98, 217.

    CAS  Google Scholar 

  63. M. Siddig, S. Radiman, L. S. Jan, S. Muniandy, Colloids Surfaces A: Physicochem. Eng. Aspects, 2006, 276, 15.

    CAS  Google Scholar 

  64. L. Johansson, A. B Wohri, G. Katona, S. Engstrom, R. Neutze, Curr. Opin. Struct. Biol., 2009, 19, 372.

    CAS  Google Scholar 

  65. B. Ericsson, K. Larsson, K. Fontanell, Biochim. Biophys. Acta, 1983, 729, 23.

    CAS  Google Scholar 

  66. P. Nollert, H. Qiuc, M. Carey, J. Rosenbusch, E. Landau, FEBS Lett., 2001, 504, 179.

    CAS  Google Scholar 

  67. P. Wadsten, A. Wuhri, A. Snijder, G. Katona, A. Gardiner, R. Cogdell, R. Neutze, S. Engström, J. Mol. Biol., 2006, 364, 44.

    CAS  Google Scholar 

  68. A. Wohri, L. Johansson, P. Wadsten-Hindrichsen, W. Wahlgren, G. Fischer, R. Horsefield, G. Katona, M. Nyblom, F. Oberg, G. Young, R. Fraser, S. Engstrom, R. Neutze, Structure, 2008, 16, 1003.

    Google Scholar 

  69. D. Libster, A. Aserin, N. Garti, J. Colloid Interface Sci., 2011, 356, 375.

    CAS  Google Scholar 

  70. V. Cherezov, J. Clogston, Y. Misquitta, W. Abdel-Gawad, M. Caffrey, Biophys. J., 2002, 83, 3393.

    CAS  Google Scholar 

  71. V. Chupin, J. Killian, B. de Kruijff, Biophys. J., 2003, 84, 2373.

    CAS  Google Scholar 

  72. M. P. Shabanov, V. A. Maidannik, G. P. Yampol’skaya, Tez. dokl., 26-go Simp. po reologii [Abstrs. of Papers, 26th Symp. on Rheology] (Tver, September 10–15, 2012), Moscow, 2012, p. 163 (in Russian).

    Google Scholar 

  73. Y. Misquitta, M. Caffrey, Biophys. J., 2003, 85, 3084.

    CAS  Google Scholar 

  74. M. Triba, D. Warschawski, P. Devaux, Biophys. J., 2005, 88, 1887.

    CAS  Google Scholar 

  75. Y. Jiang, H. Wang, J. T. Kindt, Biophys. J., 2010, 98, 2895.

    CAS  Google Scholar 

  76. K. Vinothkumar, J. Mol. Biol., 2011, 407, 232.

    CAS  Google Scholar 

  77. S. Faham, J. U. Bowie, J. Mol. Biol., 2002, 316, 1.

    CAS  Google Scholar 

  78. E. Saridakis, N. Chayen, Trends in Biotechnology, 2008, 27, 99.

    Google Scholar 

  79. E. Givargizov, A. I. Grebenko, L. A. Zadorozhnaya, V. R. Melik-Adamyan, J. Cryst. Growth, 2008, 310, 847.

    CAS  Google Scholar 

  80. E. Pechkova, C. Nicolini, J. Cryst. Growth., 2001, 231, 599.

    CAS  Google Scholar 

  81. E. Pechkova, C. Nicolini, Trends in Biotechnology, 2004, 22, 117.

    CAS  Google Scholar 

  82. E. Pechkova, R. Gebhardt, Ch. Riekel, C. Nicolini, Biophys. J., 2010, 99, 1256.

    CAS  Google Scholar 

  83. E. Pechkova, Sh. Tripathi, R. Ravelli, S. McSweeney, C. Nicolini, J. Struct. Biol., 2009, 168, 409.

    CAS  Google Scholar 

  84. E. Pechkova, G. Tropiano, Ch. Riekel, C. Nicolini, Spectrochimica Acta, Part B, 2004, 59, 1687.

    Google Scholar 

  85. T. Pham, D. Lai, D. Ji, W. Tuntiwechapikul, J. Friedman, T. Lee, Colloids Surfaces B: Biointerfaces, 2004, 34, 191.

    CAS  Google Scholar 

  86. G. Di Profio, E. Curcio, A. Cassetta, D. Lamba, E. Drioli, J. Cryst. Growth, 2003, 257, 359.

    Google Scholar 

  87. G. Di Profio, E. Curcio, E. Drioli, J. Struct. Biol., 2005, 150, 41.

    Google Scholar 

  88. A. Gugliuzza, M. Aceto, S. Simone, E. Curcio, R. Madonna, G. Di Profio, E. Drioli, Desalination, 2006, 199, 200.

    CAS  Google Scholar 

  89. S. Simone, E. Curcio, G. Di Profio, M. Ferraroni, E. Drioli, J. Membrane Science, 2006, 283, 123.

    CAS  Google Scholar 

  90. S. Stolyarova, E. Saridakis, N. E. Chayen, Y. Nemirovsky, Biophys. J., 2006, 91, 3857.

    CAS  Google Scholar 

  91. M. Takehara, K. Ino, Y. Takakusagi, H. Oshikane, O. Nureki, T. Ebina, F. Mizukami, K. Sakaguchi, Anal. Biochem., 2008, 373, 322.

    CAS  Google Scholar 

  92. N. M. Zadymova, G. P. Yampolskaya, 7th Annual European Rheology Conf. (Suzdal, Russia, May 10–14, 2011), p. 43.

  93. N. M. Zadymova, G. P. Yampol’skaya, M. V. Poteshnova, V. G. Kulichikhin, Kolloid. Zh., 2011, 73, 629 [Colloid. J. (Engl. Transl.), 2011, 73, 629].

    Google Scholar 

  94. E. Di Cola, G. Yakubov, T. Waigh, Biomacromolecules, 2008, 9, 3216.

    Google Scholar 

  95. I. N. Vyal’shin, V. A. Maidannik, D. V. Bagrov, G. P. Yampol’skaya, Abstrs. of Papers, Fifth Intern. Conf. “Progress and Trends in Bionanoscopy” (Moscow, June 18–20, 2012), Moscpw, 2012, p. 18.

    Google Scholar 

  96. K. A. Majorek, P. J. Porebski, A. Dayal, M. D. Zimmerman, K. Jablonska, A. J. Stewart, M. Chruszcz, W. Minor, Mol. Immunology, 2012, 52, 174.

    CAS  Google Scholar 

  97. S. Eggersted, M. Dietzel, M. Sommerfeld, R. Suverkrup, A. Lamprecht, Int. J. Pharmaceutics, 2012, 438, 160.

    Google Scholar 

  98. V. V. Berejnov, J. Colloid Interface Sci., 2008, 322, 246.

    CAS  Google Scholar 

  99. G. Lia, J. Lic, Ch. Bai, Da-Ch. Wang, J. of Crystal Growth, 2003, 249, 354.

    Google Scholar 

  100. V. Kopecky, Jr., V. Baumruk, Vibrational Spectrosc., 2006, 42, 184.

    CAS  Google Scholar 

  101. T. Yakhno, J. Colloid Interface Sci., 2008, 318, 225.

    CAS  Google Scholar 

  102. H. Gorr, J. Zueger, D. McAdams, J. Barnard, Colloids Surfaces B: Biointerfaces, 2013, 103, 59.

    CAS  Google Scholar 

  103. Y.-X. Liu, X.-J. Wang, J. Lu, C.-B. Ching, J. Phys. Chem. B, 2007, 111, 13971.

    CAS  Google Scholar 

  104. P. Fromme, J. Spence, Curr. Opin. Struct. Biol., 2011, 21, 509.

    CAS  Google Scholar 

  105. M. S. Hunter, D. P. DePonte, D. A. Shapiro, R. A. Kirian, X. Wang, D. Starodub, S. Marchesini, U. Weierstall, R. B. Doak, J. C. H. Spence, P. Fromme, Biophys. J., 2011, 100, 198.

    CAS  Google Scholar 

  106. R. Martin, K. Zilm, J. Magn. Reson., 2003, 165, 162.

    CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to G. P. Yampolskaya.

Additional information

Dedicated to Academician of the Russian Academy of Sciences S. M. Aldoshin on the occasion of his 60th birthday.

Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 2, pp. 0342–0358, February, 2013.

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kulichikhin, V.G., Yampolskaya, G.P. Colloid-chemical aspects of protein crystallization. Russ Chem Bull 62, 338–354 (2013). https://doi.org/10.1007/s11172-013-0045-x

Download citation

  • Received:

  • Revised:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11172-013-0045-x

Key words

Navigation