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Russian Chemical Bulletin

, Volume 58, Issue 12, pp 2478–2487 | Cite as

A new synthesis of phthalimidines

  • L. Yu. Ukhin
  • K. Yu. Suponitsky
  • L. V. Belousova
  • Zh. I. Orlova
Full Articles

Abstract

A new synthesis of phthalimidines is described. 3-Acyloxy-2-aryl- and 2-acylamino-3-acyloxyphthalimidines were prepared by the reaction of 3-arylaminophthalides or o-formylbenzoic acid acylhydrazones with acetic or propionic anhydrides. Their reactions with O-, N-, S-, and C-nucleophiles were studied. The structure of 2-acetyl(cyanoacetyl)amino-3-acetoxyindolin-1-one was confirmed by X-ray diffraction analysis.

Key words

o-formylbenzoic acid 3-arylaminophthalides o-formylbenzoic acid acylhydrazones acetic and propionic anhydrides 3-acyloxy-2-aryl-phthalimidines 2-acylamino-3-acyloxyphthalimidines X-ray diffraction analysis 

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Copyright information

© Springer Science+Business Media, Inc.  2009

Authors and Affiliations

  • L. Yu. Ukhin
    • 1
  • K. Yu. Suponitsky
    • 2
  • L. V. Belousova
    • 1
  • Zh. I. Orlova
    • 1
  1. 1.Research Institute of Physical and Organic ChemistrySouthern Federal UniversityRostov-on-DonRussian Federation
  2. 2.A. N. Nesmeyanov Institute of Organoelement CompoundsRussian Academy of SciencesMoscowRussian Federation

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