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A new synthesis of phthalimidines

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Abstract

A new synthesis of phthalimidines is described. 3-Acyloxy-2-aryl- and 2-acylamino-3-acyloxyphthalimidines were prepared by the reaction of 3-arylaminophthalides or o-formylbenzoic acid acylhydrazones with acetic or propionic anhydrides. Their reactions with O-, N-, S-, and C-nucleophiles were studied. The structure of 2-acetyl(cyanoacetyl)amino-3-acetoxyindolin-1-one was confirmed by X-ray diffraction analysis.

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Authors and Affiliations

  1. Research Institute of Physical and Organic Chemistry, Southern Federal University, 194/2 prosp. Stachki, 344090, Rostov-on-Don, Russian Federation

    L. Yu. Ukhin, L. V. Belousova & Zh. I. Orlova

  2. A. N. Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences, 28 ul. Vavilova, 119991, Moscow, Russian Federation

    K. Yu. Suponitsky

Authors
  1. L. Yu. Ukhin
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  2. K. Yu. Suponitsky
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  3. L. V. Belousova
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  4. Zh. I. Orlova
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Correspondence to L. Yu. Ukhin.

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Published in Russian in Izvestiya Akademii Nauk. Seriya Khimicheskaya, No. 12, pp. 2399–2407, December, 2009.

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Ukhin, L.Y., Suponitsky, K.Y., Belousova, L.V. et al. A new synthesis of phthalimidines. Russ Chem Bull 58, 2478–2487 (2009). https://doi.org/10.1007/s11172-009-0347-1

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  • DOI: https://doi.org/10.1007/s11172-009-0347-1

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